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Review
. 1986 Sep 15;42(9):985-7.
doi: 10.1007/BF01940701.

Stable isotopes of lithium: dissimilar biochemical and behavioral effects

K Lieberman, G J Alexander, J A Sechzer
Review

Stable isotopes of lithium: dissimilar biochemical and behavioral effects

K Lieberman et al. Experientia. .

Abstract

Lithium, which is used routinely in the treatment of mania, is composed of two stable isotopes, lithium-7 (92.58%) and lithium-6 (7.42%). Usually there is minimal physiological or biochemical differentiation between isotopes of an element, but lithium is an exception. Data derived from a variety of biochemical and behavioral experiments are reviewed to support this idea. Additionally, the clinical implications of this work are presented.

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