Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Mar 14:39:1-6.
doi: 10.1016/j.euros.2022.02.009. eCollection 2022 May.

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice

Davide Loizzo  1   2   3 , Savio D Pandolfo  1   2   4 , Fabio Crocerossa  1   2   5 , Georgi Guruli  1   2 , Matteo Ferro  6 , Asit K Paul  7 , Ciro Imbimbo  4 , Giuseppe Lucarelli  3 , Pasquale Ditonno  3 , Riccardo Autorino  1   2
Affiliations
Review

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice

Davide Loizzo et al. Eur Urol Open Sci. .

Abstract

Urachal carcinoma is a rare urological disease. The shortage of data about diagnosis and surgical treatment in literature makes it hard for clinicians to make a decision. Indeed, urachal carcinoma is an aggressive disease that requires prompt staging and treatment to ensure the best outcome for patients. We reviewed the last evidence about the management of urachal carcinoma to provide an easy-to-use guide for clinical practice.

Patient summary: Urachal carcinoma is a rare malignancy. The literature on this challenging disease remains limited. Herein, we provide a practical guide for its management from diagnosis to treatment, which in most cases requires surgical intervention or chemotherapy.

Keywords: Bladder cancer; Cystectomy; Outcomes; Treatment; Urachal carcinoma.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Management of urachal carcinoma. CT = computed tomography; 5-FU = 5-fluorouracil; PLND = pelvic lymphadenectomy; PSM = positive surgical margin.
See this image and copyright information in PMC

References

    1. Bruins H.M., Visser O., Ploeg M., Hulsbergen-van de Kaa C.A., Kiemeney L.A.L.M., Witjes J.A. The clinical epidemiology of urachal carcinoma: results of a large, population based study. J Urol. 2012;188:1102–1107. - PubMed
    1. Szarvas T., Módos O., Niedworok C., et al. Clinical, prognostic, and therapeutic aspects of urachal carcinoma—a comprehensive review with meta-analysis of 1,010 cases. Urol Oncol. 2016;34:388–398. - PubMed
    1. Yu Y.D., Ko Y.H., Kim J.W., et al. The prognosis and oncological predictor of urachal carcinoma of the bladder: a large scale multicenter cohort study analyzed 203 patients with long term follow-up. Front Oncol. 2021;11:1893. - PMC - PubMed
    1. Shao G., Xu C., Liu J., et al. Clinical, pathological, and prognostic analysis of urachal carcinoma. Urol Int. 2022;106:199–208. - PMC - PubMed
    1. Hu Z., Ke C., Liu Z., et al. Evaluation of UroVysion for urachal carcinoma detection. Front Med (Lausanne) 2020;7:437. - PMC - PubMed

LinkOut - more resources