Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Feb 17:22:38-41.
doi: 10.1016/j.jdcr.2022.02.001. eCollection 2022 Apr.

Paraneoplastic subacute cutaneous lupus erythematosus with mucositis

Affiliations
Case Reports

Paraneoplastic subacute cutaneous lupus erythematosus with mucositis

James Abbott et al. JAAD Case Rep. .
No abstract available

Keywords: ANA, antinuclear antibodies; IgG, immunoglobulin G; SCLE; SCLE, subacute cutaneous lupus erythematosus; non–small cell lung carcinoma; paraneoplastic; subacute cutaneous lupus erythematosus.

PubMed Disclaimer

Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
A, Numerous scattered erythematosus-to-pink papules and plaques with mild scale were seen throughout the neck, upper portion of the torso, and bilateral upper extremities. B, The extensive erosions and superficial ulcerations were noted through the oral mucosa, extending into the posterior aspect of the oropharynx.
Fig 2
Fig 2
A, Punch biopsy from the upper portion of the back demonstrating an atrophic epidermis with vacuolar interface dermatitis, mild perivascular lymphocytic infiltrate with rare eosinophils, and increased dermal mucin deposition. B, Biopsy of the mucosal epithelium revealed hyperkeratosis, hypergranulosis, and a moderately dense, lichenoid infiltrate that focally obscured the basal layer of the epidermis, producing dyskeratotic keratinocytes and a few colloid bodies. (A and B, Hematoxylin-eosin stain; original manifications: A, 200×; B, 100×).
Fig 3
Fig 3
Chest computed tomography revealed a left perihilar mass measuring 4.9 × 3.7 cm with significant narrowing of the upper portion of the left lobe bronchus and pulmonary vein and narrowing of the lingual pulmonary artery. The mass was abutting the left main pulmonary artery and the left atrial appendage.

References

    1. Sontheimer R.D., Thomas J.R., Gilliam J.N. Subacute cutaneous lupus erythematosus: a cutaneous marker for a distinct lupus erythematosus subset. Arch Dermatol. 1979;115(12):1409–1415. - PubMed
    1. Jarrett P., Werth V.P. A review of cutaneous lupus erythematosus: improving outcomes with a multidisciplinary approach. J Multidiscip Healthc. 2019;12:419–428. doi: 10.2147/JMDH.S179623. - DOI - PMC - PubMed
    1. Chaudhry S.I., Murphy L.A., White I.R. Subacute cutaneous lupus erythematosus: a paraneoplastic dermatosis? Clin Exp Dermatol. 2005;30(6):655–658. doi: 10.1111/j.1365-2230.2005.01900.x. - DOI - PubMed
    1. Vera-Recabarren M.A., García-Carrasco M., Ramos-Casals M., Herrero C. Comparative analysis of subacute cutaneous lupus erythematosus and chronic cutaneous lupus erythematosus: clinical and immunological study of 270 patients. Br J Dermatol. 2010;162(1):91–101. doi: 10.1111/j.1365-2133.2009.09472.x. - DOI - PubMed
    1. Callen J.P. Drug-induced subacute cutaneous lupus erythematosus. Lupus. 2010;19(9):1107–1111. doi: 10.1177/0961203310370349. - DOI - PubMed

Publication types

LinkOut - more resources