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Case Reports
. 2022 Mar 10;10(3):e05557.
doi: 10.1002/ccr3.5557. eCollection 2022 Mar.

Coronavirus disease 2019 (COVID-19) as a potential trigger for benign recurrent intrahepatic cholestasis

Turan Çalhan  1 , Elif Yivli  1
Affiliations
Case Reports

Coronavirus disease 2019 (COVID-19) as a potential trigger for benign recurrent intrahepatic cholestasis

Turan Çalhan et al. Clin Case Rep. .

Abstract

Benign recurrent intrahepatic cholestasis (BRIC) is a rare disease characterized by recurrent severe itching and jaundice. Coronavirus disease 2019 (COVID-19) is a multisystemic acute viral disease and the liver is frequently affected. Here, we wanted to present a BRIC case triggered by COVID-19 infection, discussing it together with current information.

Keywords: benign recurrent intrahepatic cholestasis; coronavirus disease 2019; liver.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIGURE 1
FIGURE 1
(A) axial magnetic resonance imaging (B) magnetic resonance cholangiopancreatography imaging. Extrahepatic and intrahepatic bile ducts appear normal in the patient. (Blue thin arrow: choledoch, yellow arrow: common bile duct, thick blue arrow: cystic duct)
See this image and copyright information in PMC

References

    1. Summerskill WHJ, Walshe JM. Benign recurrent intrahepatic obstructive cholestasis. Lancet. 1959;2:686‐690. - PubMed
    1. Ermis F, Oncu K, Ozel M, et al. Benign recurrent intrahepatic cholestasis: late initial diagnosis in adulthood. Ann Hepatol. 2010;2:207‐210. - PubMed
    1. van Ooteghem NA, Klomp LW, van Berge‐Henegouwen GP, Houwen RH. Benign recurrent intrahepatic cholestasis progressing to progressive familial intrahepatic cholestasis: low GGT cholestasis is a clinical continuum. J Hepatol. 2002;36:439‐443. - PubMed
    1. Klomp LWJ, Bull LN, Juijn JA, et al. Characterization of multiple different mutations in FIC1 assosicated with hereditary cholestasis. Hepatology. 1999;30:407A.
    1. Tygstrup N, Jensen B. Intermittent intrahepatic cholestasis of unknown etiology in five young males from the Faroe Islands. Acta Med Scand. 1969;185:523‐530. - PubMed

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