The authors reply

Hye Ju Yeo^{1

2}, Woo Hyun Cho^{1

2}

Affiliations

¹ Division of Allergy, Pulmonary and Critical care medicine, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
² Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.

Comment

Hye Ju Yeo et al. Crit Care Med. 2022.

. 2022 Apr 1;50(4):e403-e404.

doi: 10.1097/CCM.0000000000005455.

Hye Ju Yeo^{1

2}, Woo Hyun Cho^{1

2}

¹ Division of Allergy, Pulmonary and Critical care medicine, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
² Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.

No abstract available

Conflict of interest statement

The authors have disclosed that they do not have any potential conflicts of interest.

Vasopressor Initiation Within 1 Hour of Fluid Loading Is Associated With Increased Mortality in Septic Shock Patients: Analysis of National Registry Data.
Yeo HJ, Lee YS, Kim TH, Jang JH, Lee HB, Oh DK, Park MH, Lim CM, Cho WH; Korean Sepsis Alliance (KSA) Investigators. Yeo HJ, et al. Crit Care Med. 2022 Apr 1;50(4):e351-e360. doi: 10.1097/CCM.0000000000005363. Crit Care Med. 2022. PMID: 34612848
Early Vasopressor Initiation Increases Mortality in Patients With Septic Shock: Less Intensive Intervention or More Critically Ill Patients?
Wang H, He H, Shen F. Wang H, et al. Crit Care Med. 2022 Apr 1;50(4):e402-e403. doi: 10.1097/CCM.0000000000005418. Crit Care Med. 2022. PMID: 35311788 No abstract available.

1. Wang H, He H, Shen F: Early Vasopressor Initiation Increases Mortality in Patients With Septic Shock: Less Intensive Intervention or More Critically Ill Patients? Crit Care Med 2022; 50:e402–e403
1. Yeo HJ, Lee YS, Kim TH, et al; Korean Sepsis Alliance (KSA) Investigators: Vasopressor Initiation Within 1 Hour of Fluid Loading Is Associated With Increased Mortality in Septic Shock Patients: Analysis of National Registry Data. Crit Care Med 2022; 50:e351–e360
1. Permpikul C, Tongyoo S, Viarasilpa T, et al.: Early use of norepinephrine in septic shock resuscitation (CENSER). A randomized trial. Am J Respir Crit Care Med 2019; 199:1097–1105
1. Ospina-Tascón GA, Hernandez G, Alvarez I, et al.: Effects of very early start of norepinephrine in patients with septic shock: A propensity score-based analysis. Crit Care 2020; 24:52
1. Levy MM, Evans LE, Rhodes A: The surviving sepsis campaign bundle: 2018 update. Crit Care Med 2018; 46:997–1000