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Comment
. 2022 Apr 1;50(4):e407-e408.
doi: 10.1097/CCM.0000000000005421.

Bringing Hidden Biases Into Light: Comments on an Observational Study on the Use of Antifibrinolytics for Pediatric Patients With Life-Threatening Hemorrhage

Ryuji Sasaki  1 , Tetsuro Aita  2 , Hiroyuki Nagano  3 , Junichi Maehara  4 , Shinichi Okuda  5 , Toshiyuki Mizota  6 , Takashi Yoshioka  7
Affiliations
Comment

Bringing Hidden Biases Into Light: Comments on an Observational Study on the Use of Antifibrinolytics for Pediatric Patients With Life-Threatening Hemorrhage

Ryuji Sasaki et al. Crit Care Med. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Drs. Aita and Okuda disclosed work for hire. The remaining authors have disclosed that they do not have any potential conflicts of interest.

Comment in

  • The authors reply.
    Spinella PC, Leonard JC, Gaines BA, Luther JF, Wisniewski SR, Josephson CD, Leeper CM. Spinella PC, et al. Crit Care Med. 2022 Apr 1;50(4):e409-e410. doi: 10.1097/CCM.0000000000005457. Crit Care Med. 2022. PMID: 35311793 No abstract available.

Comment on

References

    1. Spinella PC, Leonard JC, Gaines BA, et al.; MAssive Transfusion epidemiology and outcomes In Children (MATIC) Investigators and BloodNet: Use of Antifibrinolytics in Pediatric Life-Threatening Hemorrhage: A Prospective Observational Multicenter Study. Crit Care Med 2022; 50:e382–e392
    1. VanderWeele TJ: Principles of confounder selection. Eur J Epidemiol 2019; 34:211–219
    1. Suissa S: Effectiveness of inhaled corticosteroids in chronic obstructive pulmonary disease: Immortal time bias in observational studies. Am J Respir Crit Care Med 2003; 168:49–53

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