Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Apr 27;9(2):e35671.
doi: 10.2196/35671.

Understanding People With Chronic Pain Who Use a Cognitive Behavioral Therapy-Based Artificial Intelligence Mental Health App (Wysa): Mixed Methods Retrospective Observational Study

Saha Meheli #  1 , Chaitali Sinha #  2 , Madhura Kadaba #  2
Affiliations

Understanding People With Chronic Pain Who Use a Cognitive Behavioral Therapy-Based Artificial Intelligence Mental Health App (Wysa): Mixed Methods Retrospective Observational Study

Saha Meheli et al. JMIR Hum Factors. .

Abstract

Background: Digital health interventions can bridge barriers in access to treatment among individuals with chronic pain.

Objective: This study aimed to evaluate the perceived needs, engagement, and effectiveness of the mental health app Wysa with regard to mental health outcomes among real-world users who reported chronic pain and engaged with the app for support.

Methods: Real-world data from users (N=2194) who reported chronic pain and associated health conditions in their conversations with the mental health app were examined using a mixed methods retrospective observational study. An inductive thematic analysis was used to analyze the conversational data of users with chronic pain to assess perceived needs, along with comparative macro-analyses of conversational flows to capture engagement within the app. Additionally, the scores from a subset of users who completed a set of pre-post assessment questionnaires, namely Patient Health Questionnaire-9 (PHQ-9) (n=69) and Generalized Anxiety Disorder Assessment-7 (GAD-7) (n=57), were examined to evaluate the effectiveness of Wysa in providing support for mental health concerns among those managing chronic pain.

Results: The themes emerging from the conversations of users with chronic pain included health concerns, socioeconomic concerns, and pain management concerns. Findings from the quantitative analysis indicated that users with chronic pain showed significantly greater app engagement (P<.001) than users without chronic pain, with a large effect size (Vargha and Delaney A=0.76-0.80). Furthermore, users with pre-post assessments during the study period were found to have significant improvements in group means for both PHQ-9 and GAD-7 symptom scores, with a medium effect size (Cohen d=0.60-0.61).

Conclusions: The findings indicate that users look for tools that can help them address their concerns related to mental health, pain management, and sleep issues. The study findings also indicate the breadth of the needs of users with chronic pain and the lack of support structures, and suggest that Wysa can provide effective support to bridge the gap.

Keywords: anxiety; artificial intelligence; chronic pain; cognitive behavioral therapy; conversational agent; depression; digital mental health; mHealth; mobile health; pain conditions; pain management; software agent.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: CS and MK are employees of Wysa Inc and own equity in the company. SM has no conflict of interest to report.

Figures

Figure 1
Figure 1
Themes of messages from users with chronic pain (N=2194).
Figure 2
Figure 2
The most frequently used conversational flows for users with chronic pain (N=2194).
See this image and copyright information in PMC

References

    1. Goldberg DS, McGee SJ. Pain as a global public health priority. BMC Public Health. 2011 Oct 06;11(1):770. doi: 10.1186/1471-2458-11-770. https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-11-770 1471-2458-11-770 - DOI - DOI - PMC - PubMed
    1. Elzahaf RA, Tashani OA, Unsworth BA, Johnson MI. The prevalence of chronic pain with an analysis of countries with a Human Development Index less than 0.9: a systematic review without meta-analysis. Curr Med Res Opin. 2012 Jul;28(7):1221–9. doi: 10.1185/03007995.2012.703132. - DOI - PubMed
    1. Mills SE, Nicolson KP, Smith BH. Chronic pain: a review of its epidemiology and associated factors in population-based studies. Br J Anaesth. 2019 Aug;123(2):e273–e283. doi: 10.1016/j.bja.2019.03.023. https://linkinghub.elsevier.com/retrieve/pii/S0007-0912(19)30227-2 S0007-0912(19)30227-2 - DOI - PMC - PubMed
    1. Tunks ER, Crook J, Weir R. Epidemiology of chronic pain with psychological comorbidity: prevalence, risk, course, and prognosis. Can J Psychiatry. 2008 Apr 01;53(4):224–34. doi: 10.1177/070674370805300403. - DOI - PubMed
    1. Bair MJ, Robinson RL, Katon W, Kroenke K. Depression and pain comorbidity: a literature review. Arch Intern Med. 2003 Nov 10;163(20):2433–45. doi: 10.1001/archinte.163.20.2433.163/20/2433 - DOI - PubMed