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. 2022 Mar 1;5(3):e223711.
doi: 10.1001/jamanetworkopen.2022.3711.

Site of Alcohol First-Pass Metabolism Among Women

Neda Seyedsadjadi  1 , M Belen Acevedo  1 , Raul Alfaro  1 , Vijay A Ramchandani  2 , Martin H Plawecki  3 , Blair Rowitz  4   5   6 , Marta Yanina Pepino  1   4   5
Affiliations

Site of Alcohol First-Pass Metabolism Among Women

Neda Seyedsadjadi et al. JAMA Netw Open. .

Erratum in

  • Error in Table.
    [No authors listed] [No authors listed] JAMA Netw Open. 2022 Apr 1;5(4):e2212773. doi: 10.1001/jamanetworkopen.2022.12773. JAMA Netw Open. 2022. PMID: 35452112 Free PMC article. No abstract available.

Abstract

This cross-sectional study compares alcohol pharmacokinetics in patients who underwent sleeve gastrectomy with control participants who did not undergo surgery.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Plawecki reported receiving grants from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) during the conduct of the study. Dr Rowitz reported receiving grants from the National Institutes of Health (NIH) during the conduct of the study. Dr Pepino reported grants from NIAAA/NIH during the conduct of the study. No other disclosures were reported.

Figures

Figure.
Figure.. Blood Alcohol Concentrations (BACs) for Sleeve Gastrectomy (SG) Group and Nonoperated Control Group
A, SG group included 12 women, and control group included 9 women. B and D, Area under the curve (AUC) for concentration-time curves for both groups. Whiskers indicate SEM. C, SG and control group participants were matched on time-to-peak BAC. Analysis was conducted among 7 women from each group. E and F, Individual BAC curves. aValue significantly different from control group at P < .05.
See this image and copyright information in PMC

References

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