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. 2021 Dec 29;55(4):450-456.
doi: 10.14744/SEMB.2021.47542. eCollection 2021.

Evaluation of the Design and Methodology of Applications to the Local Ethics Committee

Yuksel Altuntas  1 , Zeynep Yildiz Yildirmak  2 , Sarper Erdogan  3 , Deniz Seckin  3 , Asli Aksu Cerman  4 , Hande Yapislar  5 , Gulsum Onal  6 , Kubra Elcioglu  7 , Nezaket Eren  8 , Dilek Necioglu Orken  9
Affiliations

Evaluation of the Design and Methodology of Applications to the Local Ethics Committee

Yuksel Altuntas et al. Sisli Etfal Hastan Tip Bul. .

Abstract

Objectives: Proposals for scientific studies must have an original hypothesis and the appropriate design and methodology to test the premise.

Methods: This study is an evaluation of the suitability of applications submitted to a local ethics committee (EC) and the rate of publication of that research.

Results: A total of 899 files submitted for EC approval were retrospectively assessed. The EC found that the description of the methods in 44% of the applications was inaccurate, and that this type of error was most often seen in submissions from the surgical branch. In all, 52% of the applications for which we were informed about their final status were not published.

Conclusion: The results suggest that improved training in epidemiology is required to reduce the number of application errors and that new regulations could help to motivate healthcare personnel to conduct scientific research and publish their findings.

Keywords: Case-control study; epidemiology; ethics committees; interventional studies; research misconduct; thesis studies.

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Figures

Figure 1.
Figure 1.
Request for application revision by year.
See this image and copyright information in PMC

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References

    1. Hakeri H. Tıp Hukuku. 7th ed. İstanbul: Seckin; 2013.
    1. Somer P, Vatanoğlu E. Ethics committees within the scope of the regulation of clinical research. Marmara Üniversitesi Hukuk Fakültesi Hukuk Araştırmaları Dergisi. 2013;19:381–96.
    1. Ilbars H, Bebitoglu BT. How to get ethics committee approval for clinical trials in Turkey? North Clin Istanb. 2018;5:379–86. - PMC - PubMed
    1. Alev B, Genç FN. A review of the university ethics committee in Turkey. Akdeniz İİBF Journal. 2015;15:135–82.
    1. Zain S, Ab-Rahman MS, Ariffin AK, Zahrim A, Nor JM, Zain MFM, et al. Motivation for research and publication: Experience as a researcher and an academic. Procedia Social and Behavioral Sciences. 2011;18:213–9.

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