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. 2022 Jun:70:9-15.
doi: 10.1016/j.annepidem.2022.03.006. Epub 2022 Mar 19.

Cognitive impairment and low physical function among older Mexican Americans: findings from a 20-year follow-up☆

Amy Givan  1 , Brian Downer  2 , Lin-Na Chou  3 , Soham Al Snih  4
Affiliations

Cognitive impairment and low physical function among older Mexican Americans: findings from a 20-year follow-up☆

Amy Givan et al. Ann Epidemiol. 2022 Jun.

Abstract

Purpose: The aim of the study was to examine the association between cognitive impairment and low physical function over a 20-year follow-up period among older Mexican Americans.

Methods: The final sample included 1545 community-dwelling Mexican Americans age ≥ 65 years from the Hispanic Established Population for the Epidemiological Study of the Elderly, who scored moderate-high on Short Physical Performance Battery (SPPB) and were non-disabled at baseline (1993/94). Cognitive impairment was defined at each observation wave as less than equal to 21 points on the Mini Mental State Examination. General Estimating Equation was used to estimate the odds ratio of having low physical function (SPPB <7 points) over time as a function of cognitive impairment, adjusting for socio-demographics, self-reported medical conditions, body mass index, and depressive symptoms. All variables were time-varying, except sex and education.

Results: Participants with cognitive impairment had increased odds ratio of low physical function over time compared to those without cognitive impairment (Odds Ratio = 1.89; 95% Confidence Interval = 1.59-2.26, P <.0001), after controlling for all covariates.

Conclusion: Despite having moderate to high physical function and being non-disabled at baseline, participants with cognitive impairment were more likely to decline in physical function over 20-years of follow-up.

Keywords: Aging; Cognition; Longitudinal Studies; Mexican Americans; Physical functional performance.

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Figures

Figure 1.
Figure 1.
Percent of cognitive impairment versus no cognitive impairment over observational waves.
Figure 2.
Figure 2.
a) Unadjusted mean for Short Physical Performance Battery (SPPB) score as a function of cognition (MMSE<21 and MMSE ≥ 21) over a 20-year follow-up period. B) Adjusted means for SPPB score and adjusted means for all covariates as a function of cognitive impairment over a 20-year follow-up period. MMSE: Mini-Mental State Examination.
See this image and copyright information in PMC

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References

    1. Hale JM, Schneider DC, Mehta NK, Myrskylä M. Cognitive impairment in the U.S.: Lifetime risk, age at onset, and years impaired. SSM - Popul Heal. 2020;11. doi:10.1016/j.ssmph.2020.100577 - DOI - PMC - PubMed
    1. Hale JM, Schneider DC, Gampe J, Mehta NK, Myrskylä M. Trends in the risk of cognitive impairment in the United States, 1996–2014. Epidemiology. 2020;31(5):745–754. doi:10.1097/EDE.0000000000001219 - DOI - PMC - PubMed
    1. Centers of Disease Control and Prevention. Subjective Cognitive Decline — A Public Health Issue. U.S. Department of Health and Human Services. Published 2018. https://www.cdc.gov/aging/data/subjective-cognitive-decline-brief.html
    1. Herbert LE, Weuve J, Scherr PA, Evans DA. Alzheimer disease in the United States (2010–2050) estimated using the 2010 census. Am Acad Neurol. 2013;80(19):17781783. doi:10.1002/jcu.1870130614 - DOI - PMC - PubMed
    1. Roberts AW, Ogunwole SU, Blakeslee L, Rabe MA. The population 65 years and older in the United States: 2016. Am Community Surv Reports. Published online 2018:ACS-38. files/2125/Roberts et al. - 2018 - The population 65 years and older in the United St.pdf

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