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. 2022 Apr;28(4):837-840.
doi: 10.3201/eid2804.211949.

Zika Virus after the Public Health Emergency of International Concern Period, Brazil

Laith Yakob

Zika Virus after the Public Health Emergency of International Concern Period, Brazil

Laith Yakob. Emerg Infect Dis. 2022 Apr.

Abstract

More than 100,000 Zika virus cases have been reported in Brazil since the Public Health Emergency of International Concern period ended in 2016. We analyzed cases in Brazil during 2017-2021 to identify transmission trends and forecast future infection hotspots. Our results can be used for targeted interventions to reduce transmission.

Keywords: Brazil; Zika virus; arboviruses; epidemiology; statistics; vector-borne infections; viruses.

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Figures

Figure 1
Figure 1
Weekly reported Zika cases in Brazil, 2016–2020. A) Log scale of reported cases during and after the Public Health Emergency of International Concern period, which ended in November 2016. B) State-level distribution of cases for each year, as reported to the Sistema de Informação de Agravos de Notificação (9) database (bottom).
Figure 2
Figure 2
Geographic and temporal distribution of reported Zika cases after the Public Health Emergency of International Concern period, Brazil, 2017–2020. A) Consistency-weighted kernel density estimates. Contours generated with bandwidth determined by Scott’s rule adjusted by a factor of 0.7 (12), overlaid on the distribution of all case data. Points show centroids of municipalities that reported infections to the Sistema de Informação de Agravos de Notificação (9) database. B) Monthly Moran I statistic, estimated at the state level. Red indicates p<0.05; blue indicates p>0.05.
See this image and copyright information in PMC

References

    1. Yakob L, Walker T. Zika virus outbreak in the Americas: the need for novel mosquito control methods. Lancet Glob Health. 2016;4:e148–9. 10.1016/S2214-109X(16)00048-6 - DOI - PubMed
    1. European Centre for Disease Prevention and Control. Rapid risk assessment: microcephaly in Brazil potentially linked to the Zika virus epidemic. Stockholm: European Centre for Disease Prevention and Control; 2015.
    1. Hay JA, Nouvellet P, Donnelly CA, Riley S. Potential inconsistencies in Zika surveillance data and our understanding of risk during pregnancy. PLoS Negl Trop Dis. 2018;12:e0006991. 10.1371/journal.pntd.0006991 - DOI - PMC - PubMed
    1. Fischer C, Drosten C, Drexler JF. The difficulties in obtaining reliable Zika virus diagnostics. Lancet Infect Dis. 2019;19:240–1. 10.1016/S1473-3099(19)30049-0 - DOI - PubMed
    1. Moore SM, Oidtman RJ, Soda KJ, Siraj AS, Reiner RC Jr, Barker CM, et al. Leveraging multiple data types to estimate the size of the Zika epidemic in the Americas. PLoS Negl Trop Dis. 2020;14:e0008640. 10.1371/journal.pntd.0008640 - DOI - PMC - PubMed