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. 2022 Jun;108(6):995-1000.
doi: 10.1007/s00128-022-03462-1. Epub 2022 Mar 23.

General Challenges and Recommendations for the Water Quality Criteria of Endocrine Disrupting Chemicals (EDCs)

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General Challenges and Recommendations for the Water Quality Criteria of Endocrine Disrupting Chemicals (EDCs)

Daqing Liu et al. Bull Environ Contam Toxicol. 2022 Jun.

Abstract

Water quality criteria (WQC) play an important role in the environmental management of pollutants in different countries or institutions. It has been found that endocrine disrupting chemicals (EDCs) can potentially alter functions of the endocrine system and consequently cause adverse effects in aquatic organisms. Therefore, the complicated modes of action and mechanisms of EDCs should be carefully considered in WQC studies. For example, the research regarding the WQC derivation of EDCs should prioritize sensitive aquatic species in consideration of the WQC derivation. Second, the chronic toxicity of EDCs should be of utmost concern. In addition, the appropriate effects and endpoints of EDCs should be carefully selected for the WQC derivation. Moreover, it was pointed out that some new methods should be taken into consideration in the WQC studies of EDCs in the near future.

Keywords: Endocrine disrupting chemicals; Toxicological endpoints; Water quality criteria.

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References

    1. Bergman A, Heindel JJ, Jobling S, Kidd KA, Zoeller RT (2012) State of the science of endocrine disrupting chemicals. Unite Nations Environmental Programme/World Health Organization (UNEP/WHO)
    1. Caldwell DJ, Mastrocco F, Hutchinson TH, Lange R, Heijerick D, Janssen C, Anderson PD, Sumpter JP (2008) Derivation of an aquatic predicted no-effect concentration for the synthetic hormone, 17α-ethinyl estradiol. Environ Sci Technol 42:7046–7054. https://doi.org/10.1021/es800633q - DOI
    1. CCME (2007) A protocol for the derivation of water quality guidelines for the protection of aquatic life 2007. The Canadian Council of Ministers of the Environment
    1. Cherbas L, Koehler M, Cherbas P (1989) Effects of juvenile hormone on the ecdysone response of Drosophila Kc cells. Dev Genet 10:177–188. https://doi.org/10.1002/dvg.1020100307 - DOI
    1. Deforest DK, Brix KV, Tear LM, Adams WJ (2018) Multiple linear regression models for predicting chronic aluminum toxicity to freshwater aquatic organisms and developing water quality guidelines. Environ Toxicol Chem 37:80–90. https://doi.org/10.1002/etc.3922 - DOI

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