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Editorial
. 2022 Mar;20(3):161-163.
doi: 10.1080/14779072.2022.2058490. Epub 2022 Mar 28.

Il-6, Il-1β and cytokine-targeted therapy for COVID -19 patients: two more reasons to take into account statins?

Raffaella Mormile  1
Affiliations
Editorial

Il-6, Il-1β and cytokine-targeted therapy for COVID -19 patients: two more reasons to take into account statins?

Raffaella Mormile. Expert Rev Cardiovasc Ther. 2022 Mar.
No abstract available

Keywords: ARDS; COVID-19; IL-1β; IL-6; statins.

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Figures

Figure 1.
Figure 1.
IL-1Beta, IL-6 and COVID-19 hyperinflammation: two more reasons to take into account statins as adjunctive therapy?
See this image and copyright information in PMC

References

    1. Kashour T, Halwani R, Arabi YM, et al. Statins as an adjunctive therapy for COVID-19: the biological and clinical plausibility. Immunopharmacol Immunotoxicol. 2021;43(1):37–50. - PubMed
    1. McGonagle D, Sharif K, O’Regan A.. The role of cytokines including Interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease. Autoimmun Rev. 2020;19(6):102537. - PMC - PubMed
    1. Gupta A, Madhavan MV, Poterucha TJ, et al. Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19. Nat Commun. Res Sq [Preprint]. 2020. Aug 11:rs.3.rs-56210;12(1):1325. DOI: 10.21203/rs.3.rs-56210/v1. PMID: 32818209; PMCID: PMC7430584.2021. - DOI - PMC - PubMed
    1. Daniels LB, Ren J, Kumar K, et al. Relation of prior statin and anti-hypertensive use to severity of disease among patients hospitalized with COVID-19: findings from the American Heart Association’s COVID-19 cardiovascular disease registry. PLoS One. 2021;16(7):e0254635. - PMC - PubMed

    2. •• This is an interesting paper about the effects of statin administration on SARS-CoV2 infection.

    1. Masana L, Correig E, Rodríguez-Borjabad C, et al. Group OBOTSR. Effect of statin therapy on SARS-CoV-2 infection-related mortality in hospitalized patients. Eur Heart J Cardiovasc Pharmacother. 2022;8(2):157–164. - PMC - PubMed

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