Multicenter Study

. 2022 Feb 28;29(3):1488-1500.

doi: 10.3390/curroncol29030125.

What Should Be the Topics of a Prospective Study on Ovarian Masses in Children?-Results of a Multicenter Retrospective Study and a Scoping Literature Review

Justyna Łuczak¹, Maciej Bagłaj², Piotr Dryjański¹, Alicja Kalcowska^{1

3}, Nastazja Banaszyk-Pucała⁴, Maria Boczar⁵, Krzysztof Dymek⁶, Małgorzata Fryczek⁷, Kaja Giżewska-Kacprzak⁸, Wojciech Górecki⁷, Andrzej Grabowski⁹, Anna Gregor¹⁰, Maria Jabłońska¹¹, Grzegorz Kowalewski¹¹, Magdalena Lewandowska¹², Maria Małowiecka¹³, Anna Ogorzałek¹⁴, Magdalena Pękalska¹⁵, Aneta Piotrowska-Gall¹⁶, Mateusz Porębski¹⁷, Marek Siewiński¹⁸, Dariusz Patkowski¹

Affiliations

¹ Pediatric Surgery and Urology Department, Wroclaw Medical University, 50-367 Wrocław, Poland.
² Department of Propedeutic of Pediatrics and Rare Diseases, Wroclaw Medical University, 50-367 Wrocław, Poland.
³ Pediatric Surgery Department, Dolnośląski Szpital Specjalistyczny im. T. Marciniaka, 54-049 Wrocław, Poland.
⁴ Department of Pediatric Surgery, Urology and Traumatology, Poznan University of Medical Sciences, 61-701 Poznań, Poland.
⁵ Clinic of Pediatric Surgery, Institute of Mother and Child, 01-211 Warszawa, Poland.
⁶ Department of General and Oncological Pediatric Surgery for Children and Adolescents, Nicolaus Copernicus University, Ludwik Rydygier Collegium Medicum, 85-067 Bydgoszcz, Poland.
⁷ Pediatric Surgery Department, Jagiellonian University Medical College, 31-008 Kraków, Poland.
⁸ Department of Pediatric and Oncological Surgery, Urology and Hand Surgery, Pomeranian Medical University, 70-204 Szczecin, Poland.
⁹ Department of Children Developmental Defects and Traumatology, Medical University of Silesia, 40-055 Katowice, Poland.
¹⁰ Pediatric Surgery and Urology Department, Zielona Góra Medical University, 65-046 Zielona Góra, Poland.
¹¹ Department of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute, 04-730 Warszawa, Poland.
¹² Department of Pediatric Surgery and Oncology, Central University Hospital, Medical University of Lodz, 90-647 Łódź, Poland.
¹³ Pediatric Surgery Department, Children's Hospital in Dziekanów Leśny, 05-092 Dziekanów Leśny, Poland.
¹⁴ Pediatric Surgery and Urology Clinic, Medical College of Rzeszów University, 65-959 Rzeszów, Poland.
¹⁵ Chair and Department of Pediatric Surgery and Traumatology, Medical University of Lublin, 20-059 Lublin, Poland.
¹⁶ Department of Pediatric Surgery, Urology and Traumatology, Collegium Medicum, Jan Kochanowski University, 25-369 Kielce, Poland.
¹⁷ Pediatric Surgery and Urology Clinic, Medical University of Silesia, 40-055 Katowice, Poland.
¹⁸ Pediatric Surgery Department, Opole University Hospital, 45-052 Opole, Poland.

PMID: 35323325
PMCID: PMC8946882
DOI: 10.3390/curroncol29030125

Multicenter Study

What Should Be the Topics of a Prospective Study on Ovarian Masses in Children?-Results of a Multicenter Retrospective Study and a Scoping Literature Review

Justyna Łuczak et al. Curr Oncol. 2022.

. 2022 Feb 28;29(3):1488-1500.

doi: 10.3390/curroncol29030125.

Authors

Affiliations

¹ Pediatric Surgery and Urology Department, Wroclaw Medical University, 50-367 Wrocław, Poland.
² Department of Propedeutic of Pediatrics and Rare Diseases, Wroclaw Medical University, 50-367 Wrocław, Poland.
³ Pediatric Surgery Department, Dolnośląski Szpital Specjalistyczny im. T. Marciniaka, 54-049 Wrocław, Poland.
⁴ Department of Pediatric Surgery, Urology and Traumatology, Poznan University of Medical Sciences, 61-701 Poznań, Poland.
⁵ Clinic of Pediatric Surgery, Institute of Mother and Child, 01-211 Warszawa, Poland.
⁶ Department of General and Oncological Pediatric Surgery for Children and Adolescents, Nicolaus Copernicus University, Ludwik Rydygier Collegium Medicum, 85-067 Bydgoszcz, Poland.
⁷ Pediatric Surgery Department, Jagiellonian University Medical College, 31-008 Kraków, Poland.
⁸ Department of Pediatric and Oncological Surgery, Urology and Hand Surgery, Pomeranian Medical University, 70-204 Szczecin, Poland.
⁹ Department of Children Developmental Defects and Traumatology, Medical University of Silesia, 40-055 Katowice, Poland.
¹⁰ Pediatric Surgery and Urology Department, Zielona Góra Medical University, 65-046 Zielona Góra, Poland.
¹¹ Department of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute, 04-730 Warszawa, Poland.
¹² Department of Pediatric Surgery and Oncology, Central University Hospital, Medical University of Lodz, 90-647 Łódź, Poland.
¹³ Pediatric Surgery Department, Children's Hospital in Dziekanów Leśny, 05-092 Dziekanów Leśny, Poland.
¹⁴ Pediatric Surgery and Urology Clinic, Medical College of Rzeszów University, 65-959 Rzeszów, Poland.
¹⁵ Chair and Department of Pediatric Surgery and Traumatology, Medical University of Lublin, 20-059 Lublin, Poland.
¹⁶ Department of Pediatric Surgery, Urology and Traumatology, Collegium Medicum, Jan Kochanowski University, 25-369 Kielce, Poland.
¹⁷ Pediatric Surgery and Urology Clinic, Medical University of Silesia, 40-055 Katowice, Poland.
¹⁸ Pediatric Surgery Department, Opole University Hospital, 45-052 Opole, Poland.

PMID: 35323325
PMCID: PMC8946882
DOI: 10.3390/curroncol29030125

Abstract

Purpose: to determine management problems of ovarian masses in girls in order to form a baseline for prospective randomized studies of the established topics and quality improvement of our management.

Materials and methods: We performed a national analysis of clinical aspects of ovarian masses in girls operated on in Poland, analyzed retrospectively medical files of all consecutive patients aged 0-18 who underwent surgeries for ovarian lesions between 2012 and 2017 at 17 pediatric surgical departments and complemented the analysis with a scoping review of a recent primary research related to ovarian masses in children.

Results: The study group comprised 595 patients. Forty-four (7.39%) girls were diagnosed with malignant tumors. The overall preservation rate was 64.54%. The analysis revealed that positive tumor markers (OR = 10.3), lesions larger than 6 cm (OR = 4.17) and solid mass on ultrasound examination (OR = 5.34) are interdependent variables differentiating malignant tumors from non-malignant lesions (X42 = 79.1; p = 0.00000). Our scoping review revealed 10 major branches of research within the topic of ovarian masses in pediatric population.

Conclusions: We have developed an overview of the field with the emphasis on the local environment. Our next step is a multi-institutional prospective study of a quality improvement project implementation based on the obtained knowledge.

Keywords: child; evidence-based practice; ovarian cysts; ovarian masses; ovarian neoplasms; prospective studies; quality improvement; scoping study; therapeutics.

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Conflict of interest statement

The authors declare no conflict of interest.

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What Should Be the Topics of a Prospective Study on Ovarian Masses in Children?-Results of a Multicenter Retrospective Study and a Scoping Literature Review

Affiliations

What Should Be the Topics of a Prospective Study on Ovarian Masses in Children?-Results of a Multicenter Retrospective Study and a Scoping Literature Review

Authors

Affiliations

Abstract

Conflict of interest statement

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