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Review
. 2022 Sep 29;75(6):1092-1096.
doi: 10.1093/cid/ciac233.

Screening for Ocular Candidiasis Among Patients With Candidemia: Is It Time to Change Practice?

Matthew O'Donnell  1 , Andrew W Eller  2 , Evan L Waxman  2 , Cornelius J Clancy  3 , M Hong Nguyen  1   3
Affiliations
Review

Screening for Ocular Candidiasis Among Patients With Candidemia: Is It Time to Change Practice?

Matthew O'Donnell et al. Clin Infect Dis. .

Abstract

Ocular candidiasis (OC) complicates approximately 10% of candidemia and carries potentially severe morbidity. There are conflicting recommendations about the need for routine funduscopic examinations of candidemic patients. Indirect funduscopy is accurate and safe in diagnosing OC, and positive findings change recommended treatment. However, conclusive evidence that treatment changes improve outcomes is lacking. Bringing perspectives as infectious diseases physicians and ophthalmologists, we review controversies about OC and endorse routine screening during candidemia. We acknowledge difficulties in obtaining inpatient ophthalmologic consults and recommend studies to evaluate digital fundus photography and teleophthalmology as an alternative to funduscopic examinations by ophthalmologists in asymptomatic patients.

Keywords: Candida endophthalmitis; candidemia; chorioretinitis; funduscopy; ocular candidiasis.

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Conflict of interest statement

Potential conflicts of interest. All authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

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