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. 2022 Apr;70(4):1216-1221.
doi: 10.4103/ijo.IJO_2371_21.

Outcomes and favourable prognostic factors in patients of phacomorphic and phacolytic glaucoma managed by manual small-incision cataract surgery: A retrospective study

Shivkumar Chandrashekharan  1 , Sabyasachi Chakrabarty  2 , Meghana Tanwar  3 , Bharadwaja Madhuvarasu  1 , Mohammed Sithiq Uduman  4 , Rengappa Ramakrishnan  5
Affiliations

Outcomes and favourable prognostic factors in patients of phacomorphic and phacolytic glaucoma managed by manual small-incision cataract surgery: A retrospective study

Shivkumar Chandrashekharan et al. Indian J Ophthalmol. 2022 Apr.

Abstract

Purpose: To evaluate the outcomes and identify favorable prognostic factors in patients of phacomorphic (PMG) and phacolytic glaucoma (PLG) managed by manual small-incision cataract surgery (MSICS).

Methods: The medical records of patients with PMG/PLG who had undergone MSICS in a tertiary eye hospital between September 2014 and August 2018 were retrospectively reviewed. Regression analyses were conducted to identify the predictors associated with intraoperative or postoperative complications and a favorable final outcome at 1 month, namely, a best-corrected visual acuity (BCVA) of 6/18 or better and an intraocular pressure (IOP) of <21 mm Hg. P < 0.05 was considered statistically significant.

Results: The records of 209 patients with PMG and 279 patients with PLG were eligible for the review. The mean preoperative IOP for PMG and PLG were 43.15 ± 12.9 and 40.05 ± 12.0 mm Hg, respectively (P = 0.006). A younger age (<60 years) was associated with a lower risk of severe postoperative inflammation in both PMG and PLG [OR = 0.45 (0.21-0.99); P = 0.047 and OR = 0.44 (0.23-0.83); P = 0.011, respectively]. There was no significant difference in the final mean logMAR BCVA (P = 0.21) and IOP (P = 0.36) in the two groups. The likelihood of a final IOP of <21 mm Hg was significant for symptoms less than a week [OR = 3.52 (1.2-10.2); P = 0.02] in PMG and for absence of vitreous disturbance [OR = 35.0 (3.8-325.7); P = 0.002] in PLG. A BCVA of 6/18 or better was strongly associated with symptoms for less than a week [OR = 1.58 (1.0-2.4); P = 0.043] and absence of vitreous disturbance [OR = 23.53 (5.1-108.0); P < 0.001].

Conclusion: Early diagnosis and management can translate to good outcomes in PMG and PLG.

Keywords: Manual small-incision cataract surgery; phacolytic glaucoma; phacomorphic glaucoma.

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Conflict of interest statement

None

References

    1. Angra SK, Pradhan R, Garg SP. Cataract induced glaucoma--An insight into management. Indian J Ophthalmol. 1991;39:97–101. - PubMed
    1. Braganza A, Thomas R, George T, Mermoud A. Management of phacolytic glaucoma: Experience of 135 cases. Indian J Ophthalmol. 1998;46:139–43. - PubMed
    1. Senthil S, Chinta S, Rao HL, Choudhari NS, Pathak-Ray V, Mandal AK, et al. Comparison of cataract surgery alone versus cataract surgery combined with trabeculectomy in the management of phacomorphic glaucoma. J Glaucoma. 2016;25:e209–13. - PubMed
    1. Kothari R, Tathe S, Gogri P, Bhandari A. Lens-induced glaucoma: The need to spread awareness about early management of cataract among rural population. ISRN Ophthalmol 2013. 2013 581727. - PMC - PubMed
    1. Yaakub A, Abdullah N, Siti Raihan I, Ahmad Tajudin LS. Lens-induced glaucoma in a tertiary centre in northeast of Malaysia. Malays Fam Physician. 2014;9:48–52. - PMC - PubMed