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Review
. 2022 Feb 24;11(3):452.
doi: 10.3390/antiox11030452.

Algal Metabolites Can Be an Immune Booster against COVID-19 Pandemic

Ajay Kumar  1 , Rahul Prasad Singh  2 , Indrajeet Kumar  2 , Priya Yadav  2 , Sandeep Kumar Singh  3 , Kaushalendra  4 , Prashant Kumar Singh  5 , Rajan Kumar Gupta  2 , Shiv Mohan Singh  2 , Mahipal Singh Kesawat  6 , Ganesh Dattatraya Saratale  7 , Sang-Min Chung  8 , Manu Kumar  8
Affiliations
Review

Algal Metabolites Can Be an Immune Booster against COVID-19 Pandemic

Ajay Kumar et al. Antioxidants (Basel). .

Abstract

The world has faced the challenges of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) for the last two years, first diagnosed at the end of 2019 in Wuhan and widely distributed worldwide. As a result, the WHO has proclaimed the illness brought on by this virus to be a global pandemic. To combat COVID-19, researcher communities continuously develop and implement rapid diagnoses, safe and effective vaccinations and other alternative therapeutic procedures. However, synthetic drug-related side effects and high costs have piqued scientists' interest in natural product-based therapies and medicines. In this regard, antiviral substances derived from natural resources and some medicines have seen a boom in popularity. For instance, algae are a rich source of compounds such as lectins and sulfated polysaccharides, which have potent antiviral and immunity-boosting properties. Moreover, Algae-derived compounds or metabolites can be used as antibodies and vaccine raw materials against COVID-19. Furthermore, some algal species can boost immunity, reduce viral activity in humans and be recommended for usage as a COVID-19 preventative measure. However, this field of study is still in its early stages of development. Therefore, this review addresses critical characteristics of algal metabolites, their antioxidant potential and therapeutic potential in COVID-19.

Keywords: COVID-19; SARS-CoV-2; algae; antioxidants; antiviral; metabolites.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Bioactive metabolites extracted from algae and their possible approach to treating or preventing COVID-19.
Figure 2
Figure 2
Molecular mechanism of seaweed polysaccharides (SPs) used as a potential biotherapeutic agent against SARS-CoV-2. The figure was modified from [45].
Figure 3
Figure 3
An overview of the diversity of physiologically active antioxidants produced in algae and their possible therapeutic and biological potential.
See this image and copyright information in PMC

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References

    1. Brown E.D., Wright G.D. Antibacterial drug discovery in the resistance era. Nature. 2016;529:336–343. doi: 10.1038/nature17042. - DOI - PubMed
    1. Singh A.K., Singh S.K., Singh P.P., Srivastava A.K., Pandey K.D., Kumar A., Yadav H. Biotechnological aspects of plants metabolites in the treatment of ulcer: A new perspective. Biotechnol. Rep. 2018;18:e00256. doi: 10.1016/j.btre.2018.e00256. - DOI - PMC - PubMed
    1. Chen H.Y., Lin Y.H., Huang J.W., Chen Y.C. Chinese herbal medicine network and core treatments for allergic skin diseases: Implications from a nationwide database. J. Ethnopharmacol. 2015;168:260–267. doi: 10.1016/j.jep.2015.04.002. - DOI - PubMed
    1. Kumar M., Singh S.K., Singh P.P., Singh V.K., Rai A.C., Srivastava A.K., Shukla L., Kesawat M.S., Kumar Jaiswal A., Chung S.-M., et al. Potential Anti-Mycobacterium tuberculosis Activity of Plant Secondary Metabolites: Insight with Molecular Docking Interactions. Antioxidants. 2021;10:1990. doi: 10.3390/antiox10121990. - DOI - PMC - PubMed
    1. Gurjar H.P., Irchhaiya D.R., Vermas D.A. Review on some medicinal plants with antidiabetic activity. J. Drug Deliv. Ther. 2016;6:45–51. doi: 10.22270/jddt.v6i2.1199. - DOI