Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Mar 1;10(3):464.
doi: 10.3390/healthcare10030464.

Implementing an Antimicrobial Stewardship Programme to Improve Adherence to a Perioperative Prophylaxis Guideline

Nehad J Ahmed  1   2 , Ziyad S Almalki  1 , Abdullah A Alfaifi  1 , Ahmed M Alshehri  1 , Abdullah K Alahmari  1 , Emad Elazab  3 , Alaa Almansour  4 , Abdul Haseeb  5 , Mohamed F Balaha  1   6 , Amer H Khan  2
Affiliations

Implementing an Antimicrobial Stewardship Programme to Improve Adherence to a Perioperative Prophylaxis Guideline

Nehad J Ahmed et al. Healthcare (Basel). .

Abstract

Perioperative antimicrobial prophylaxis is effective in reducing the rate of surgical site infections (SSIs); however, non-adherence to surgical antimicrobial prophylaxis protocols can lead to several negative outcomes. We performed a before-and-after intervention study with the aim of improving the process outcome, including adherence to guidelines. Another objective of this study was to investigate improvement in patient outcomes as a result of adherence to a surgical antimicrobial prophylaxis programme. The indicators of improved patient outcomes were a reduction in overall SSI rate and the decreased cost of antibiotics. SSI rate was calculated as a percentage by dividing the number of SSIs by the total number of surgeries and then multiplying the value obtained by 100%. The interventions implemented in the surgical antimicrobial prophylaxis programme included establishment of a guideline, educational sessions, and a monthly revision of prescriptions. Our findings show that implementation of the interventions resulted in reduced antibiotic consumption, a considerable decrease in the cost of prophylaxis, and a decrease in the incidence of SSIs.

Keywords: antimicrobial stewardship; surgical antimicrobial prophylaxis; surgical site infection.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Geubbels E.L., Mintjes-de Groot A.J., van den Berg J.M.J., de Boer A.S. An operating surveillance system of surgical-site infections in The Netherlands: Results of the PREZIES national surveillance network. Infect. Control Hosp. Epidemiol. 2000;21:311–318. doi: 10.1086/501762. - DOI - PubMed
    1. European Centre for Disease Prevention and Control Healthcare-Associated Infections: Surgical Site Infections—Annual Epidemiological Report for 2017. [(accessed on 5 July 2021)]; Available online: https://www.ecdc.europa.eu/en/publications-data/healthcare-associated-in....
    1. Wang Z., Chen J., Wang P., Jie Z., Jin W., Wang G., Li J., Ren J. Surgical site infection after gastrointestinal surgery in China: A multicenter prospective study. J. Surg. Res. 2019;240:206–218. doi: 10.1016/j.jss.2019.03.017. - DOI - PubMed
    1. Woods R.K., Dellinger E.P. Current guidelines for antibiotic prophylaxis of surgical wounds. Am. Fam. Phys. 1998;57:2731–2740. - PubMed
    1. Polk H.C., Jr., Christmas A.B. Prophylactic antibiotics in surgery and surgical wound infections. Am. Surg. 2000;66:105–111. - PubMed

LinkOut - more resources