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Review
. 2022 Mar 10;9(3):389.
doi: 10.3390/children9030389.

Interventional Pain Management for the Pediatric Cancer Patient: A Literature Review

Christina Le-Short  1 , Kavya Katragadda  2 , Neil Nagda  3 , David Farris  1 , Marianne Halphen Gelter  1
Affiliations
Review

Interventional Pain Management for the Pediatric Cancer Patient: A Literature Review

Christina Le-Short et al. Children (Basel). .

Abstract

This literature review examines the use of interventional treatments for pain management in pediatric cancer patients. While interventional procedures may be effective in cancer pain management, these procedures are infrequently employed in pediatric cohorts. This underutilization of interventional procedures may be supported by a deficit in randomized, controlled studies and literature regarding their role in pediatric cancer populations. Particularly because literature on the efficacy of interventional treatments in adult populations may not directly translate to pediatric populations, more research about the role of interventional procedures in managing pediatric cancer pain is necessary for a strengthened understanding of pediatric cancer pain treatment.

Keywords: cancer pain; interventional pain; pain interventions; pediatric cancer pain; pediatric pain.

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Conflict of interest statement

The authors have no conflict of interest.

References

    1. Lu Q., Krull K.R., Leisenring W., Owen J.E., Kawashima T., Tsao J.C.I., Zebrack B., Mertens A., Armstrong G.T., Stovall M., et al. Pain in long-term adult survivors of childhood cancers and their siblings: A report from the Childhood Cancer Survivor Study. Pain. 2011;152:2616–2624. doi: 10.1016/j.pain.2011.08.006. - DOI - PMC - PubMed
    1. Schulte F.S.M., Patton M., Alberts N.M., Kunin-Batson A., Olson-Bullis B.A., Forbes C., Russell K.B., Neville A., Heathcote L.C., Karlson C.W., et al. Pain in long-term survivors of childhood cancer: A systematic review of the current state of knowledge and a call to action from the Children’s Oncology Group. Cancer. 2020;127:35–44. doi: 10.1002/cncr.33289. - DOI - PMC - PubMed
    1. World Health Organization . WHO Guidelines on Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses. World Health Organization; Geneva, Switzerland: 2012. - PubMed
    1. Constance J.E., Campbell S.C., Somani A.A., Yellepeddi V., Owens K.H., Sherwin C.M.T. Pharmacokinetics, pharmacodynamics and pharmacogenetics associated with nonsteroidal anti-inflammatory drugs and opioids in pediatric cancer patients. Expert Opin. Drug Metab. Toxicol. 2017;13:715–724. doi: 10.1080/17425255.2017.1329415. - DOI - PubMed
    1. Tutelman P.R., Chambers C.T., Stinson J.N., Parker J.A., Fernandez C.V., Witteman H.O., Nathan P.C., Barwick M., Campbell F., Jibb L.A., et al. Pain in Children with Cancer: Prevalence, Characteristics, and Parent Management. Clin. J. Pain. 2018;34:198–206. doi: 10.1097/AJP.0000000000000531. - DOI - PubMed

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