Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb 20:46:100966.
doi: 10.1016/j.nmni.2022.100966. eCollection 2022 Mar.

Lausannevirus bilevel set-points

Linda Mueller  1 , Hector Moreno  1 , Stefan Kunz  1 , Gilbert Greub  1
Affiliations

Lausannevirus bilevel set-points

Linda Mueller et al. New Microbes New Infect. .
No abstract available

Keywords: Dormancy; giant viruses; latency; lausannevirus; set-points; switches.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
One month of Lausannevirus co-culture in A. castellanii. Viral load distribution of 8 subcultures of Lausannevirus (A-H) co-cultured in A.castellanii during one month, in triplicate. Confluent A.castellanii were infected with Lausannevirus subcultures, incubated and filtered three times per week. DNA extraction and specific Lausannevirus RT-PCR were assessed on each filtrate.
See this image and copyright information in PMC

References

    1. Koonin E.V., Yutin N. Evolution of the large nucleocytoplasmic DNA viruses of eukaryotes and convergent origins of viral gigantism. Adv Virus Res. 2019;103:167–202. - PubMed
    1. Thomas V., Bertelli C., Collyn F., Casson N., Telenti A., Goesmann A., et al. Lausannevirus, a giant amoebal virus encoding histone doublets. Environ Microbiol. 2011;13(6):1454–1466. - PubMed
    1. Singh A., Weinberger L.S. Stochastic gene expression as a molecular switch for viral latency. Curr Opinion in Microbiol. 2009;12(4):460–466. - PMC - PubMed
    1. Mueller L., Bertelli C., Pillonel T., Salamin N., Greub G. One year genome evolution of Lausannevirus in allopatric versus sympatric conditions. Genome Biology and Evolution. 2017;9(6):1432–1449. - PMC - PubMed
    1. Weinberger L.S., Burnett J.C., Toettcher J.E., Arkin A.P., Schaffer D.V. Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell. 2005;122(2):169–182. - PubMed

LinkOut - more resources