Alpha-thalassemia in blacks: genetic and clinical aspects and interactions with the sickle hemoglobin gene
- PMID: 3533181
Alpha-thalassemia in blacks: genetic and clinical aspects and interactions with the sickle hemoglobin gene
Abstract
Recent advances in molecular genetics have permitted detailed study of the human alpha-globin genes and the causes of alpha-thalassemia. In this review, we examine the causes of alpha-thalassemia in the black population and the consequences of the interactions between alpha-thalassemia and structural hemoglobin variants.
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