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Meta-Analysis
. 2022 Jun;32(6):2047-2055.
doi: 10.1007/s11695-022-06021-z. Epub 2022 Mar 24.

Hypoglycemia in Pregnancies Following Gastric Bypass-a Systematic Review and Meta-analysis

Louise L Stentebjerg  1   2 , Lene R Madsen  3   4   5 , René K Støving  6 , Claus B Juhl  7   8   9   10 , Christina A Vinter  7   8   11 , Lise Lotte T Andersen  8   11 , Kristina Renault  12 , Dorte M Jensen  7   8   11
Affiliations
Meta-Analysis

Hypoglycemia in Pregnancies Following Gastric Bypass-a Systematic Review and Meta-analysis

Louise L Stentebjerg et al. Obes Surg. 2022 Jun.

Abstract

The aims of this systematic review were to identify the prevalence of hypoglycemia among pregnant women treated with gastric bypass, and risk factors of hypoglycemic events in pregnancy. We searched MEDLINE, EMBASE, Cochrane, and Scopus databases from inception to April 6, 2021. Six studies investigating glucose metabolism in pregnancy following gastric bypass were included (n = 330). As assessed by the oral glucose tolerance test and continuous glucose monitoring, 57.6% (95% CI [40.1, 75.1]) of women with gastric bypass were exposed to hypoglycemia during pregnancy. No studies performed the mixed meal test, and no studies reported on risk factors associated with hypoglycemia. Further studies are required to determine the magnitude of hypoglycemia in these women's everyday-life using continuous glucose monitoring and mixed meal test.

Keywords: Bariatric surgery; Continuous glucose monitoring; Hypoglycemia; Meta-analysis; Mixed meal test; Obesity; Oral glucose tolerance test; Pregnancy; Roux-en-Y gastric bypass; Systematic review.

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References

    1. Brown WA, Kow L, Shikora S, et al. The 6th IFSO Global Registry Report. https://www.ifso.com/pdf/ifso-6th-registry-report-2021.pdf ; 2021.
    1. Yearly statement of number of bariatric surgeries performed in Denmark [Internet]. 2019 [cited August 30th, 2019]. Available from: https://www.esundhed.dk/Emner/Operationer-og-diagnoser/Fedmeoperationer .
    1. Colquitt JL, Pickett K, Loveman E, Frampton GK. Surgery for weight loss in adults. Cochrane Database of Systematic Reviews. 2014(8).
    1. Azagury DE, Morton JM. Bariatric surgery: overview of procedures and outcomes. Endocrinol Metab Clin North Am. 2016;45(3):647–56. - DOI
    1. Kwong W, Tomlinson G, Feig DS. Maternal and neonatal outcomes after bariatric surgery; a systematic review and meta-analysis: do the benefits outweigh the risks? Am J Obstet Gynecol. 2018;218(6):573–80. - DOI

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