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. 2022 Apr 11;40(4):353-355.
doi: 10.1016/j.ccell.2022.03.001. Epub 2022 Mar 24.

Seed or soil: Tracing the immune subsets in metastatic tumors

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Seed or soil: Tracing the immune subsets in metastatic tumors

Xuexin Yu et al. Cancer Cell. .
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Abstract

Mapping the tumor-infiltrating immune subsets to an origin of malignancy or tissue niche is important for designing effective immunotherapies, yet it remains a challenging task. In this issue of Cancer Cell, Liu et al. pieced together this puzzle through a comprehensive single-cell analysis of colorectal cancer patients with liver metastases.

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Declaration of interests The authors declare no competing interests.

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