Seed or soil: Tracing the immune subsets in metastatic tumors
- PMID: 35334203
- DOI: 10.1016/j.ccell.2022.03.001
Seed or soil: Tracing the immune subsets in metastatic tumors
Abstract
Mapping the tumor-infiltrating immune subsets to an origin of malignancy or tissue niche is important for designing effective immunotherapies, yet it remains a challenging task. In this issue of Cancer Cell, Liu et al. pieced together this puzzle through a comprehensive single-cell analysis of colorectal cancer patients with liver metastases.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Immune phenotypic linkage between colorectal cancer and liver metastasis.Cancer Cell. 2022 Apr 11;40(4):424-437.e5. doi: 10.1016/j.ccell.2022.02.013. Epub 2022 Mar 17. Cancer Cell. 2022. PMID: 35303421
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