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Editorial
. 2022 Mar 7:13:838604.
doi: 10.3389/fimmu.2022.838604. eCollection 2022.

Editorial: Generating and Sustaining Stable Autoantigen-Specific CD4 and CD8 Regulatory T Cells in Lupus

Syamal K Datta  1 , David A Horwitz  2   3 , Ciriaco A Piccirillo  4   5 , Antonio La Cava  5   6
Affiliations
Editorial

Editorial: Generating and Sustaining Stable Autoantigen-Specific CD4 and CD8 Regulatory T Cells in Lupus

Syamal K Datta et al. Front Immunol. .
No abstract available

Keywords: T regulatory cells; autoimmunity; graft-versus-host disease; humanized mice; immune tolerance; nanoparticle (NP); peptide epitopes; systemic lupus erythematosus.

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Conflict of interest statement

DAH is the CEO of and holds stock in General Nanotherapeutics, LLC. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Comment on

  • Editorial on the Research Topic Generating and Sustaining Stable Autoantigen-specific CD4 and CD8 Regulatory T Cells in Lupus

References

    1. Linker-Israeli M, Bakke AC, Kitridou RC, Gendler S, Gillis S, Horwitz DA. Defective Production of Interleukin 1 and Interleukin 2 in Patients With Systemic Lupus Erythematosus (SLE). J Immunol (Baltimore Md: 1950) (1983) 130(6):2651–5. - PubMed
    1. Ohtsuka K, Gray JD, Stimmler MM, Toro B, Horwitz DA. Decreased Production of TGF-Beta by Lymphocytes From Patients With Systemic Lupus Erythematosus. J Immunol (1998) 160:2539–45. - PubMed
    1. Sakaguchi S. Taking Regulatory T Cells Into Medicine. J Exp Med (2021) 218(6):e20210831. doi: 10.1084/jem.20210831 - DOI - PMC - PubMed
    1. Valencia X, Yarboro C, Illei G, Lipsky PE. Deficient CD4+CD25high T Regulatory Cell Function in Patients With Active Systemic Lupus Erythematosus. J Immunol (2007) 178(4):2579–88. doi: 10.4049/jimmunol.178.4.2579 - DOI - PubMed
    1. Miao J, Zhu P. Functional Defects of Treg Cells: New Targets in Rheumatic Diseases, Including Ankylosing Spondylitis. Curr Rheumatol Rep (2018) 20(5):30. doi: 10.1007/s11926-018-0729-1 - DOI - PubMed

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