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. 2022 Jan-Feb;25(1):114-119.
doi: 10.4103/aian.aian_711_21. Epub 2022 Feb 8.

Epidemiology of Young Stroke in the Ludhiana Population-Based Stroke Registry

Monika Singla  1 , Gagandeep Singh  1 , Paramdeep Kaur  2 , Jeyaraj D Pandian  3
Affiliations

Epidemiology of Young Stroke in the Ludhiana Population-Based Stroke Registry

Monika Singla et al. Ann Indian Acad Neurol. 2022 Jan-Feb.

Abstract

Objective: The objective of the study was to determine incidence, risk factors, and short-term outcomes of young stroke in Ludhiana city, Northwest India.

Methods: Data were collected on first-ever stroke in patients of age ≥18 years, from hospitals, diagnostic imaging centers, general practitioners, and municipal corporation during March 2011-March 2013 in Ludhiana city, using the World Health Organization Stepwise Approach to Surveillance (WHO STEPS). Outcome was documented using the modified Rankin Scale at 28 days.

Results: Of 2948 patients, 700 (24%) were in the age group 18-49 years. Annual incidence in this age group was 46/100,000 person-years (95% confidence interval [CI], 41-51/100,000). Hypertension (84%), diabetes mellitus (48%), and atrial fibrillation (AF) (12%) were found more common in >49 years age group, as compared with 18-49 years age group. Drug abuse (8.7% vs. 6% in age >49 years; P = 0.04) and tobacco intake (8.7% vs. 5.6% in age >49 years; P = 0.02) was more common in young people, that is, 18-49 years age group in comparison to older patients, >49 years age group. Recovery was better in younger subjects (60% vs. 46% in age >49 years P < 0.001). In a multivariable analysis, younger people were more often literate (odds ratio [OR] 2.52; 95% CI, 1.68-3.77; P < 0.001), employed (OR 3.92; 95% CI, 2.20-5.21; P < 0.001), and 374 (60%) had good clinical outcome, modified Rankin Scale <2 at 28 days follow-up as compared with 938 (46%) older patients (OR 1.52; 95% CI, 1.15-2.00; P = 0.003).

Conclusion: Hypertension, diabetes mellitus, drug addiction, and tobacco intake were significantly associated with young stroke. Outcome was also better in younger people.

Keywords: Population-based registry; World Health Organization Stepwise Approach to Surveillance Approach (WHO STEP); lower-and middle-income countries; young stroke.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Recruitment algorithm
See this image and copyright information in PMC

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