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. 2022 Sep;21(3):e171-e178.
doi: 10.1016/j.clcc.2022.02.005. Epub 2022 Mar 3.

Impact of the COVID-19 Pandemic on Colorectal Cancer Care in the Netherlands: A Population-based Study

Joyce Meijer  1 , Marloes A G Elferink  2 , Jolanda C van Hoeve  1 , Jeroen Buijsen  3 , Felice van Erning  2 , Iris D Nagtegaal  4 , Pieter J Tanis  5 , Geraldine R Vink  6 , Miriam L Wumkes  7 , Ignace H J T de Hingh  8 , Sabine Siesling  9 ; On-behalf-of-the-COVID-and-Cancer-NL Consortium
Affiliations

Impact of the COVID-19 Pandemic on Colorectal Cancer Care in the Netherlands: A Population-based Study

Joyce Meijer et al. Clin Colorectal Cancer. 2022 Sep.

Abstract

Introduction: The COVID-19 pandemic disrupted health care services worldwide. In the Netherlands, the first confirmed COVID-19 infection was on February 27, 2020. We aimed to investigate the impact of the pandemic on colorectal cancer care in the Netherlands.

Methods: Colorectal cancer patients who were diagnosed in 25 hospitals in weeks 2 to 26 of the year 2020 were selected from the Netherlands Cancer Registry (NCR) and divided in 4 periods. The average number of patients treated per type of initial treatment was analyzed by the Mantel-Haenszel test adjusted for age. Median time between diagnosis and treatment and between (neo)adjuvant therapy and surgery were analyzed by the Mann Whitney test. Percentages of (acute) resection, stoma and (neo)adjuvant therapy were compared using the Chi-squared test.

Results: In total, 1,653 patients were included. The patient population changed during the COVID-19 pandemic regarding higher stage and more clinical presentation with ileus at time of diagnosis. Slight changes were found regarding type of initial treatment. Median time between diagnosis and treatment decreased on average by 4.5 days during the pandemic. The proportion of colon cancer patients receiving a stoma significantly increased with 6.5% during the pandemic. No differences were found in resection rate and treatment with (neo)adjuvant therapy.

Conclusion: Despite the disruptive impact of the COVID-19 pandemic on global health care, the impact on colorectal cancer care in the Netherlands was limited.

Keywords: (neo)adjuvant therapy; Colon; Rectal; Resection; Stoma; Treatment.

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Conflict of interest statement

Disclosure The authors have stated that they have no conflicts of interest.

Figures

Figure 1A
Figure 1A
Average number of colon cancer patients of all ages treated per week, per tumor stage and per type of initial treatment.
Figure 1B
Figure 1B
Average number of rectal cancer patients of all ages treated per week, per tumor stage and per type of initial treatment.
See this image and copyright information in PMC

References

    1. Liang W, Guan W, Chen R, et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. The lancet oncology. 2020;21:335–337. - PMC - PubMed
    1. National Institute of Public Health and the Environment. 2020. Patiënt met nieuw coronavirus in Nederland.https://www.rivm.nl/nieuws/patient-met-nieuw-coronavirus-in-nederland [Accessed june 21, 2021] Available from:
    1. Central Government . 2020. Maart 2020: Maatregelen tegen verspreiding coronavirus, intelligente lockdown.https://www.rijksoverheid.nl/onderwerpen/coronavirus-tijdlijn/maart-2020... [Accessed May 21, 2021]. Available from:
    1. de Jonge L, Worthington J, van Wifferen F, et al. Impact of the COVID-19 pandemic on faecal immunochemical test-based colorectal cancer screening programmes in Australia, Canada, and the Netherlands: a comparative modelling study. The Lancet Gastroenterol & Hepatol. 2021 - PMC - PubMed
    1. Morris EJ, Goldacre R, Spata E, et al. Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study. The Lancet Gastroenterology & Hepatology. 2021 - PMC - PubMed