Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 May 15;205(10):1253-1254.
doi: 10.1164/rccm.202202-0292LE.

Reply to Akin et al.: High Renin Concentrations in Severe COVID-19 Are Indicative for a Hypo-Renin-Angiotensin-System State

Daniel E Leisman  1 , Arnav Mehta  1   2   3   4 , B Taylor Thompson  1   2 , Nir Hacohen  1   2   3 , Michael R Filbin  1   2   3 , Marcia B Goldberg  1   2   3
Affiliations
Comment

Reply to Akin et al.: High Renin Concentrations in Severe COVID-19 Are Indicative for a Hypo-Renin-Angiotensin-System State

Daniel E Leisman et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Comment on

  • Alveolar, Endothelial, and Organ Injury Marker Dynamics in Severe COVID-19.
    Leisman DE, Mehta A, Thompson BT, Charland NC, Gonye ALK, Gushterova I, Kays KR, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Parry BA, Villani AC, Sade-Feldman M, Hacohen N, Filbin MR, Goldberg MB. Leisman DE, et al. Am J Respir Crit Care Med. 2022 Mar 1;205(5):507-519. doi: 10.1164/rccm.202106-1514OC. Am J Respir Crit Care Med. 2022. PMID: 34878969 Free PMC article.
  • High Renin Concentrations in Severe COVID-19 Are Indicative for a Hypo-Renin-Angiotensin-System State.
    Akin S, Schriek P, van Nieuwkoop C, Neuman RI, Verdonk K, Danser AHJ. Akin S, et al. Am J Respir Crit Care Med. 2022 May 15;205(10):1252-1253. doi: 10.1164/rccm.202112-2781LE. Am J Respir Crit Care Med. 2022. PMID: 35348428 Free PMC article. No abstract available.

References

    1. Leisman DE, Mehta A, Thompson BT, Charland NC, Gonye ALK, Gushterova I, et al. Alveolar, endothelial, and organ injury marker dynamics in severe COVID-19. Am J Respir Crit Care Med . 2022;205:507–519. - PMC - PubMed
    1. Bellomo R, Wunderink RG, Szerlip H, English SW, Busse LW, Deane AM, et al. Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock. Crit Care . 2020;24:43. - PMC - PubMed
    1. Leisman DE, Mastroianni F, Fisler G, Shah S, Hasan Z, Narasimhan M, et al. Physiologic response to angiotensin II treatment for coronavirus disease 2019-induced vasodilatory shock: a retrospective matched cohort study. Crit Care Explor . 2020;2:e0230. - PMC - PubMed
    1. Leisman DE, Fernandes TD, Bijol V, et al. Impaired angiotensin II type 1 receptor signaling contributes to sepsis induced acute kidney injury. Kidney Int . 2021;99:148–160. - PMC - PubMed
    1. Akin S, Schriek P, van Nieuwkoop C, Neuman RI, Meynaar I, van Helden EJ, et al. A low aldosterone/renin ratio and high soluble ACE2 associate with COVID-19 severity. J Hypertens . 2022;40:606–614. - PMC - PubMed