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Comparative Study
. 1978 Apr 17;160(3):319-24.
doi: 10.1007/BF00332975.

Ability of chloramphenicol to suppress phenotypically some bacterial mutations

V Kuhrová, B Koukalová, J Reich
Comparative Study

Ability of chloramphenicol to suppress phenotypically some bacterial mutations

V Kuhrová et al. Mol Gen Genet. .

Abstract

Chloramphenicol (CLP) at slightly inhibitory concentrations (3-5 microgram/ml) suppresses the inhibition of DNA synthesis and cell division caused by the temperature sensitive mutation dnaE486 at the nonpermissive temperature. Some other mutations can also be phenotypically suppressed by CLP. A similar effect is shown by chlortetracycline. Phenotypic suppression is caused by both these drugs in different cases than by streptomycin.

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