Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682

Adem Y Dawed¹, Sook Wah Yee², Kaixin Zhou¹, Nienke van Leeuwen³, Yanfei Zhang⁴, Moneeza K Siddiqui¹, Amy Etheridge⁵, Federico Innocenti⁵, Fei Xu⁶, Josephine H Li^{7

8}, Joline W Beulens⁹, Amber A van der Heijden^{10

11}, Roderick C Slieker^{3

10}, Yu-Chuan Chang², Josep M Mercader^{7

8}, Varinderpal Kaur^{7

8}, John S Witte¹², Ming Ta Michael Lee⁴, Yoichiro Kamatani¹³, Yukihide Momozawa¹³, Michiaki Kubo¹³, Colin N A Palmer¹, Jose C Florez^{7

8

14}, Monique M Hedderson¹², Leen M 't Hart^{3

15

16}, Kathleen M Giacomini^{2

17}, Ewan R Pearson¹; for MetGen Plus, for the DIRECT Consortium

Affiliations

¹ Population Health and Genomics, School of Medicine, University of Dundee, Dundee, U.K.
² Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA.
³ Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
⁴ Genomic Medicine Institute, Geisinger, Danville, PA.
⁵ Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
⁶ Division of Research, Kaiser Permanente Northern California, Oakland, CA.
⁷ Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
⁸ Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.
⁹ Amsterdam UMC, location VUmc, Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
¹⁰ Amsterdam UMC, location VUmc, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
¹¹ Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, the Netherlands.
¹² Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA.
¹³ RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
¹⁴ Department of Medicine, Harvard Medical School, Boston, MA.
¹⁵ Section Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.
¹⁶ Department of General Practice Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
¹⁷ Institute for Human Genetics, University of California, San Francisco, San Francisco, CA.

PMID: 35349657
PMCID: PMC9016729
DOI: 10.2337/dci21-0066

Comment

Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682

Adem Y Dawed et al. Diabetes Care. 2022.

. 2022 Apr 1;45(4):e82-e83.

doi: 10.2337/dci21-0066.

Authors

Affiliations

¹ Population Health and Genomics, School of Medicine, University of Dundee, Dundee, U.K.
² Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA.
³ Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
⁴ Genomic Medicine Institute, Geisinger, Danville, PA.
⁵ Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
⁶ Division of Research, Kaiser Permanente Northern California, Oakland, CA.
⁷ Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
⁸ Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA.
⁹ Amsterdam UMC, location VUmc, Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
¹⁰ Amsterdam UMC, location VUmc, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
¹¹ Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, the Netherlands.
¹² Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA.
¹³ RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
¹⁴ Department of Medicine, Harvard Medical School, Boston, MA.
¹⁵ Section Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.
¹⁶ Department of General Practice Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
¹⁷ Institute for Human Genetics, University of California, San Francisco, San Francisco, CA.

PMID: 35349657
PMCID: PMC9016729
DOI: 10.2337/dci21-0066

No abstract available

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Comment on

Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas.
Dawed AY, Yee SW, Zhou K, van Leeuwen N, Zhang Y, Siddiqui MK, Etheridge A, Innocenti F, Xu F, Li JH, Beulens JW, van der Heijden AA, Slieker RC, Chang YC, Mercader JM, Kaur V, Witte JS, Lee MTM, Kamatani Y, Momozawa Y, Kubo M, Palmer CNA, Florez JC, Hedderson MM, 't Hart LM, Giacomini KM, Pearson ER; for MetGen Plus, for the DIRECT Consortium; MetGen Plus investigators:. Dawed AY, et al. Diabetes Care. 2021 Dec;44(12):2673-2682. doi: 10.2337/dc21-1152. Epub 2021 Oct 4. Diabetes Care. 2021. PMID: 34607834 Free PMC article.
Comment on Dawed et al. Genome-Wide Meta-Analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682.
Wang K, Shi M, Yang A, Tomlinson B, Chan JCN, Chow E. Wang K, et al. Diabetes Care. 2022 Apr 1;45(4):e80-e81. doi: 10.2337/dc21-2428. Diabetes Care. 2022. PMID: 35349650 Free PMC article. No abstract available.

References

1. Wang K, Mai S, Yang A, et al. . Comment on Dawed et al. Genome-wide meta-analysis identifies genetic variants associated with glycemic response to sulfonylureas. Diabetes Care 2021;44:2673–2682 (Letter). Diabetes Care 2022;45:e80–e81 - PMC - PubMed
1. Dawed AY, Yee SW, Zhou K, et al. .; for MetGen Plus, for the DIRECT Consortium . Genome-wide meta-analysis identifies genetic variants associated with glycemic response to sulfonylureas. Diabetes Care 2021;44:2673–2682 - PMC - PubMed
1. Zheng HX, Huang Y, Frassetto LA, Benet LZ. Elucidating rifampin’s inducing and inhibiting effects on glyburide pharmacokinetics and blood glucose in healthy volunteers: unmasking the differential effects of enzyme induction and transporter inhibition for a drug and its primary metabolite. Clin Pharmacol Ther 2009;85:78–85 - PMC - PubMed
1. Yang F, Xiong X, Liu Y, et al. . CYP2C9 and OATP1B1 genetic polymorphisms affect the metabolism and transport of glimepiride and gliclazide. Sci Rep 2018;8:10994. - PMC - PubMed
1. van de Steeg E, Greupink R, Schreurs M, et al. . Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1. Drug Metab Dispos 2013;41:592–601 - PubMed

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Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682

Affiliations

Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682

Authors

Affiliations

Comment on

References

Publication types

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LinkOut - more resources

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