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. 2022 Mar 4;10(2):147-151.
doi: 10.5599/admet.1271. eCollection 2022.

Recent advances and challenges in antibacterial drug development

Valeria Gigante  1 , Hatim Sati  1 , Peter Beyer  1
Affiliations

Recent advances and challenges in antibacterial drug development

Valeria Gigante et al. ADMET DMPK. .
No abstract available

Keywords: Antimicrobial Resistance; Public Health; Research and Development; WHO Pipeline.

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Conflict of interest statement

Conflict of interest: No conflict of interest is declared by the authors.

References

    1. Murray C.J., Ikuta K.S., Sharara F., Swetschinski L., Aguilar G.R., Gray A., Han C., Bisignano C., Rao P., Wool E., Johnson S.C.. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. The Lancet 399 (2022) P629-655. https://doi.org/10.1016/S0140-6736(21)02724-0. 10.1016/S0140-6736(21)02724-0 - DOI - PMC - PubMed
    1. Butler M.S., Gigante V., Sati H., Paulin S., Al-Sulaiman L., Rex J.H., Fernandes P., Arias C.A., Paul M., Thwaites G.E., Czaplewski L.. Analysis of the clinical pipeline of treatments for drug resistant bacterial infections: despite progress, more action is needed. Antimicrobial Agents and Chemotherapy (2022) https://doi.org/10.1128/AAC.01991-21. 10.1128/AAC.01991-21 - DOI - PMC - PubMed
    1. Prioritization of pathogens to guide discovery, research, and development of new antibiotics for drug-resistant bacterial infections, including tuberculosis. World Health Organization; 2017. https://apps.who.int/iris/handle/10665/311820.
    1. Antibiotics Currently in Global Clinical Development, Pew’s antibiotic resistance project communication, Updated: March 9, 2021. Available via: Antibiotics Currently in Global Clinical Development | The Pew Charitable Trusts (pewtrusts.org) (Last accessed 01/27/2022).
    1. 2020 Antibacterial agents in clinical and preclinical development: an overview and analysis. Geneva: World Health Organization; 2021. Licence: CC BY-NC-SA 3.0 IGO.

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