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Case Reports
. 2022 Mar 1;30(1):119-123.
doi: 10.53854/liim-3001-14. eCollection 2022.

The serious threat of late presenters HIV-infected patients in the context of the COVID-19 pandemic

Pierluigi Brugnaro  1 , Erika Morelli  1 , Francesca Cattelan  1 , Andrea Petrucci  1 , Francesco Colombo  1 , Sara Caputo  1 , Licia Laurino  2 , Sandro Panese  1
Affiliations
Case Reports

The serious threat of late presenters HIV-infected patients in the context of the COVID-19 pandemic

Pierluigi Brugnaro et al. Infez Med. .

Abstract

The impact of current SARS-CoV-2 pandemic on the healthcare services had serious consequences, especially for the most fragile populations such as HIV-positive subjects. In the period April to September 2020 we reported four cases of HIV-infected late presenters with an AIDS-defining life-threatening condition that, due to the difficult access to the hospital during the pandemic, were characterized by a delayed HIV recognition and institution of correct treatment. Even after two decades of highly active antiretroviral therapy late presenters HIV-infected patients still represent a serious clinical challenge.

Keywords: AIDS; COVID-19; late presenters; opportunistic infections.

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Conflict of interest statement

Conflict of interest The Authors state that they do not have any conflict of interest to declare.

Figures

Figure 1
Figure 1
Chest Computed Tomography: bilateral diffuse interstitial tickening with “ground-glass” and “crazy pavement” pattern.
Figure 2
Figure 2
Brain autoptic findings showing an infiltrate composed of large lymphoid cells; hematoxylin-eosin staining x20 (A); immunoreactive for CD-20 (B) and for Epstein Barr virus by in situ hybridization staining (C).
See this image and copyright information in PMC

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