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Case Reports
. 2022 Mar 29;15(3):e248018.
doi: 10.1136/bcr-2021-248018.

Type I cryoglobulinaemia leading to bilateral above-the-knee amputations

Michael Duplisea  1 , Lee Jamison  2 , Eben Lichtman  1
Affiliations
Case Reports

Type I cryoglobulinaemia leading to bilateral above-the-knee amputations

Michael Duplisea et al. BMJ Case Rep. .
No abstract available

Keywords: haematology (incl blood transfusion); malignant and benign haematology.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A) Ischaemic changes involving the helix, scapha and antihelix of the left ear. (B) Ischaemic lesion on the left lateral aspect of the tongue. (C) Ischaemic lesions involving the right hand and wrist.
Figure 2
Figure 2
Extensive ischaemic lesions involving the bilateral lower extremities.
See this image and copyright information in PMC

References

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    1. Sidana S, Rajkumar SV, Dispenzieri A, et al. . Clinical presentation and outcomes of patients with type 1 monoclonal cryoglobulinemia. Am J Hematol 2017;92:668–73. 10.1002/ajh.24745 - DOI - PMC - PubMed
    1. Muchtar E, Magen H, Gertz MA. How I treat cryoglobulinemia. Blood 2017;129:289–98. 10.1182/blood-2016-09-719773 - DOI - PubMed
    1. Vacula I, Ambrózy E, Makovník M, et al. . Cryoglobulinemia manifested by gangraene of almost all fingers and toes. Int Angiol 2010;29:560–4. - PubMed
    1. Suyama Y, Kishimoto M, Togashi S, et al. . Cold-associated painful purple digits due to type I cryoglobulinemia. Vasc Med 2017;22:69. 10.1177/1358863X16668265 - DOI - PubMed

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