Hypospadias: lessons learned. An overview of incidence, epidemiology, surgery, research, complications, and outcomes

doi:10.1038/s41443-022-00563-7

Review

. 2023 Feb;35(1):61-66.

doi: 10.1038/s41443-022-00563-7. Epub 2022 Mar 29.

Hypospadias: lessons learned. An overview of incidence, epidemiology, surgery, research, complications, and outcomes

Dan Wood^{1

2}, Duncan Wilcox³

Affiliations

¹ University of Colorado, Aurora, CO, USA. daniel.wood@childrenscolorado.org.
² Center for Childrens' Surgery Children's Hospital Colorado, Aurora, CO, USA. daniel.wood@childrenscolorado.org.
³ Center for Childrens' Surgery Children's Hospital Colorado, Aurora, CO, USA.

PMID: 35352016
DOI: 10.1038/s41443-022-00563-7

Review

Hypospadias: lessons learned. An overview of incidence, epidemiology, surgery, research, complications, and outcomes

Dan Wood et al. Int J Impot Res. 2023 Feb.

. 2023 Feb;35(1):61-66.

doi: 10.1038/s41443-022-00563-7. Epub 2022 Mar 29.

Authors

Dan Wood^{1

2}, Duncan Wilcox³

Affiliations

¹ University of Colorado, Aurora, CO, USA. daniel.wood@childrenscolorado.org.
² Center for Childrens' Surgery Children's Hospital Colorado, Aurora, CO, USA. daniel.wood@childrenscolorado.org.
³ Center for Childrens' Surgery Children's Hospital Colorado, Aurora, CO, USA.

PMID: 35352016
DOI: 10.1038/s41443-022-00563-7

Abstract

Hypospadias is a common condition and familiar, though sometimes challenging territory for the pediatric urologist. This review is a summary of hypospadias incidence, epidemiology, surgery, research, and complications intended for the non-specialist. It outlines the history, the principles of surgery for hypospadias, and the long-term outcomes.

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References

1. Springer A, van den Heijkant M, Baumann S. Worldwide prevalence of hypospadias. J Pediatr Urol. 2016;12:152.e1–7. https://doi.org/10.1016/j.jpurol.2015.12.002 . - DOI - PubMed
1. Bergman JE, Laone M, Vrijeid M, Pierini A, Nijman RJ, Addor MC, et al. Epidemiology of hypospadias in Europe: a registry-based study. World J Urol. 2015;33:2159–67. https://doi.org/10.1007/s00345-015-1507-6 . - DOI - PubMed - PMC
1. van der Zanden LF, van Rooij IA, Feitz WF, Franke B, Knoers NV, Roeleveld N, et al. Aetiology of hypospadias: a systematic review of genes and environment. Hum Reprod Update. 2012;18:260–83. https://doi.org/10.1093/humupd/dms002 . - DOI - PubMed
1. Ea V, Bergounoux A, Philbert P, Servat-Fauconnet N, Faure A, Breaud J, et al. How far should we explore hypospadias? Next-generation sequencing applied to a large cohort of hypospadiac patients. Eur Urol. 2021;79:507–15. https://doi.org/10.1016/j.eururo.2020.12.036 . - DOI - PubMed
1. Hsieh MH, Breyer BN, Eisenberg ML, Baskin LS. Associations among hypospadias, cryptorchidism, anogenital distance, and endocrine disruption. Curr Urol Rep. 2008;9:137–42. https://doi.org/10.1007/s11934-008-0025-0 . - DOI - PubMed

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[1] Springer A, van den Heijkant M, Baumann S. Worldwide prevalence of hypospadias. J Pediatr Urol. 2016;12:152.e1–7. https://doi.org/10.1016/j.jpurol.2015.12.002 . - DOI - PubMed

[2] Springer A, van den Heijkant M, Baumann S. Worldwide prevalence of hypospadias. J Pediatr Urol. 2016;12:152.e1–7. https://doi.org/10.1016/j.jpurol.2015.12.002 . - DOI - PubMed

[3] Bergman JE, Laone M, Vrijeid M, Pierini A, Nijman RJ, Addor MC, et al. Epidemiology of hypospadias in Europe: a registry-based study. World J Urol. 2015;33:2159–67. https://doi.org/10.1007/s00345-015-1507-6 . - DOI - PubMed - PMC

[4] Bergman JE, Laone M, Vrijeid M, Pierini A, Nijman RJ, Addor MC, et al. Epidemiology of hypospadias in Europe: a registry-based study. World J Urol. 2015;33:2159–67. https://doi.org/10.1007/s00345-015-1507-6 . - DOI - PubMed - PMC

[5] van der Zanden LF, van Rooij IA, Feitz WF, Franke B, Knoers NV, Roeleveld N, et al. Aetiology of hypospadias: a systematic review of genes and environment. Hum Reprod Update. 2012;18:260–83. https://doi.org/10.1093/humupd/dms002 . - DOI - PubMed

[6] van der Zanden LF, van Rooij IA, Feitz WF, Franke B, Knoers NV, Roeleveld N, et al. Aetiology of hypospadias: a systematic review of genes and environment. Hum Reprod Update. 2012;18:260–83. https://doi.org/10.1093/humupd/dms002 . - DOI - PubMed

[7] Ea V, Bergounoux A, Philbert P, Servat-Fauconnet N, Faure A, Breaud J, et al. How far should we explore hypospadias? Next-generation sequencing applied to a large cohort of hypospadiac patients. Eur Urol. 2021;79:507–15. https://doi.org/10.1016/j.eururo.2020.12.036 . - DOI - PubMed

[8] Ea V, Bergounoux A, Philbert P, Servat-Fauconnet N, Faure A, Breaud J, et al. How far should we explore hypospadias? Next-generation sequencing applied to a large cohort of hypospadiac patients. Eur Urol. 2021;79:507–15. https://doi.org/10.1016/j.eururo.2020.12.036 . - DOI - PubMed

[9] Hsieh MH, Breyer BN, Eisenberg ML, Baskin LS. Associations among hypospadias, cryptorchidism, anogenital distance, and endocrine disruption. Curr Urol Rep. 2008;9:137–42. https://doi.org/10.1007/s11934-008-0025-0 . - DOI - PubMed

[10] Hsieh MH, Breyer BN, Eisenberg ML, Baskin LS. Associations among hypospadias, cryptorchidism, anogenital distance, and endocrine disruption. Curr Urol Rep. 2008;9:137–42. https://doi.org/10.1007/s11934-008-0025-0 . - DOI - PubMed

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Hypospadias: lessons learned. An overview of incidence, epidemiology, surgery, research, complications, and outcomes

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Hypospadias: lessons learned. An overview of incidence, epidemiology, surgery, research, complications, and outcomes

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