Hypervitaminosis D and nephrocalcinosis: too much of a good thing?

Mandy Wan^{1

2}, Jignesh Patel^{3

4}, Greta Rait⁵, Rukshana Shroff⁶

Affiliations

¹ Pharmacy Department, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK. mandy.wan@gstt.nhs.uk.
² Institute of Pharmaceutical Science, King's College London, London, UK. mandy.wan@gstt.nhs.uk.
³ Institute of Pharmaceutical Science, King's College London, London, UK.
⁴ Department of Haematological Medicine, King's College Hospital Foundation NHS Trust, London, UK.
⁵ Research Department of Primary Care and Population Health, University of College London, London, UK.
⁶ UCL Great Ormond Street Hospital for Children and Institute of Child Health, London, UK.

Editorial

Mandy Wan et al. Pediatr Nephrol. 2022 Oct.

. 2022 Oct;37(10):2225-2229.

doi: 10.1007/s00467-022-05513-5. Epub 2022 Mar 29.

Mandy Wan^{1

2}, Jignesh Patel^{3

4}, Greta Rait⁵, Rukshana Shroff⁶

¹ Pharmacy Department, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK. mandy.wan@gstt.nhs.uk.
² Institute of Pharmaceutical Science, King's College London, London, UK. mandy.wan@gstt.nhs.uk.
³ Institute of Pharmaceutical Science, King's College London, London, UK.
⁴ Department of Haematological Medicine, King's College Hospital Foundation NHS Trust, London, UK.
⁵ Research Department of Primary Care and Population Health, University of College London, London, UK.
⁶ UCL Great Ormond Street Hospital for Children and Institute of Child Health, London, UK.

No abstract available

Comment on

Nephrocalcinosis in children who received high-dose vitamin D.
Lin TH, Lu HJ, Lin CH, Lee MD, Chang BP, Lin CC, Tsai JD. Lin TH, et al. Pediatr Nephrol. 2022 Oct;37(10):2471-2478. doi: 10.1007/s00467-022-05512-6. Epub 2022 Mar 29. Pediatr Nephrol. 2022. PMID: 35352189

1. Theodoratou E, Tzoulaki I, Zgaga L, Ioannidis JPA (2014) Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ 348:g2035 - PubMed - PMC - DOI
1. Scientific Advisory Committee on Nutrition (2016) SACN vitamin D and health report. https://assets.publishing.service.gov.uk/government/uploads/system/uploa... . Accessed 15 Feb 2022
1. Bilinski K, Talbot P (2014) Vitamin D supplementation in Australia: implications for the development of supplementation guidelines. J Nutr Metab 2014:e374208 - DOI
1. Kantor ED, Rehm CD, Du M, White E et al (2016) Trends in dietary supplement use among US adults from 1999–2012. JAMA 316:1464–1474 - PubMed - PMC - DOI
1. Wan M, Horsfall LJ, Basatemur E, Patel JP et al (2019) Vitamin D prescribing in children in UK primary care practices: a population-based cohort study. BMJ Open 9:e031870 - PubMed - PMC - DOI