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. 2022 Nov 1;31(6):554-557.
doi: 10.1097/CEJ.0000000000000745. Epub 2022 Mar 29.

Progress in prostate cancer prevention

Gabriele Cozzi  1 , Gennaro Musi  1   2 , Matteo Ferro  1 , Antonio Cioffi  1 , Ottavio de Cobelli  1   2 , Giovanni Corso  2   3
Affiliations

Progress in prostate cancer prevention

Gabriele Cozzi et al. Eur J Cancer Prev. .

Abstract

After lung, prostate cancer is the second most frequently diagnosed cancer and fourth in cancer-related mortality. The etiology is largely unknown and no clear risk factors have been identified. Primary prevention is therefore challenging. Also, secondary prevention, screening, in large populations is difficult. Germline mutations are implicated in hereditary prostate cancer, accounting for about 10% of screened men. Currently, only prostate-specific antigen test is adopted for early detection but is considered insufficient to further improve prevention and care. In this opinion article, we discuss novel diagnostic biomarkers and imaging tools, along with more promising targeted prostate biopsies.

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