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Case Reports
. 2022 Feb 24;14(2):e22570.
doi: 10.7759/cureus.22570. eCollection 2022 Feb.

Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report

Leonardo Enciso  1   2 , Rafael L Aragón-Mendoza  3 , Laura A León  4 , Carrie G Torres-Torres  4
Affiliations
Case Reports

Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report

Leonardo Enciso et al. Cureus. .

Abstract

The management of pregnancy and delivery in patients with Glanzmann thrombasthenia requires platelet transfusion and recombinant activated factor VII. We report two successful pregnancies in a single patient and propose a protocol for monitoring and treatment. The urgent need for controlled trials and other epidemiological studies is also underscored.

Keywords: glanzmann thrombasthenia; platelet refractoriness; platelet transfusion; pregnancy; recombinant activated factor vii.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

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