Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Mar 25:9:2333794X221084070.
doi: 10.1177/2333794X221084070. eCollection 2022.

Adverse Neonatal Outcomes and Associated Risk Factors: A Case-Control Study

Affiliations

Adverse Neonatal Outcomes and Associated Risk Factors: A Case-Control Study

Yeneneh Ayalew Workineh et al. Glob Pediatr Health. .

Abstract

Background: Adverse neonatal outcomes have a significant effect on perinatal and neonatal survival and the risk of developmental disabilities and illnesses throughout future lives. Hence, the objective of this study was to identify adverse neonatal outcomes and associated risk factors.

Method: Institutional based unmatched case-control study was conducted among 206 neonates. Neonates who had adverse outcomes were cases with their index mothers and those neonates who hadn't had adverse outcomes were controls with their index mothers. Sociodemographic, potential neonatal risk factors, and clinical data were taken from the mothers and medical records. Data were entered into Epi Info v7 and analyzed using SPSS v23. Bivariate and multivariable logistic regression analyses were used to adjust for confounding factors of adverse neonatal outcomes. Frequencies, means, standard deviations, percentages, and cross-tabulations were used to summarize the descriptive statistics of the data.

Results: In this study, low birth weight (61.5%), preterm birth (57.7%), and low Apgar score at fifth minutes (53.9%) were the major identified adverse neonatal outcomes. Based on the multivariable logistic regression analysis, rural place of residence (AOR = 5.992 to 95% CI [1.011-35.809]), low monthly income (AOR = 4.364), middle monthly income (AOR = 4.364), and emergency cesarean section (AOR = 9.969) were the potential risk factors for adverse neonatal outcomes.

Conclusions: The adverse neonatal outcomes & the risk factors identified in this research have the potential to harm the health of the neonates. Thus, it needs emphasis to tackle the problems and save the life of the newborn through better and strengthened ANC follow-up, accesses to health care.

Keywords: Mekelle City; adverse neonatal outcome; neonate; risk factors.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Adverse neonatal outcome among cases in hospitals of Mekelle City, Northern Ethiopia, 2015. n = 52.

References

    1. Ezechi OC, David AN. Overview of Global Perinatal Mortality. InTech; 2012.
    1. Lucas AO, Stoll BJ, Bale JR. Improving Birth Outcomes: Meeting the Challenge in the Developing World. National Academies Press; 2003. - PubMed
    1. Lawn JE, Blencowe H, Oza S, et al.. Every newborn: progress, priorities, and potential beyond survival. Lancet. 2014;384(9938):189-205. - PubMed
    1. Nkwabong E, Fomulu JN, Hamida A, et al.. The risk of adverse maternal and neonatal outcomes in cameroonian primiparous women aged more than 26 years. Clin Mother Child Health. 2011;8(1):1-4.
    1. Kiondo P, Tumwesigye NM, Wandabwa J, Wamuyu-Maina G, Bimenya GS, Okong P. Adverse neonatal outcomes in women with pre-eclampsia in Mulago Hospital, Kampala, Uganda: a cross-sectional study. Pan Afr Med J. 2014;17 Suppl 1(1):7. - PMC - PubMed

LinkOut - more resources