Predicting the Future: Machine-Based Learning for MRD Prognostication
- PMID: 35357437
- DOI: 10.1158/1078-0432.CCR-22-0219
Predicting the Future: Machine-Based Learning for MRD Prognostication
Abstract
The prognostic significance of minimal residual disease (MRD) detection in multiple myeloma is well established. Understanding factors that predict for MRD negativity, such as tumor burden, cytogenetic, and immune-related biomarkers, may enable us to improve outcome prediction at diagnosis, and in the future move toward tailored treatment approaches. See related article by Guerrero et al., p. 2598.
©2022 American Association for Cancer Research.
Comment on
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A Machine Learning Model Based on Tumor and Immune Biomarkers to Predict Undetectable MRD and Survival Outcomes in Multiple Myeloma.Clin Cancer Res. 2022 Jun 13;28(12):2598-2609. doi: 10.1158/1078-0432.CCR-21-3430. Clin Cancer Res. 2022. PMID: 35063966
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