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Comment
. 2022 Jun 1;205(11):1365-1366.
doi: 10.1164/rccm.202112-2852LE.

Change in Lung Function after Initiation of Elexacaftor-Tezacaftor-Ivacaftor: Do Not Forget Anatomy!

Clémence Martin  1   2   3 , Lucile Regard  1   2   3 , Guillaume Chassagnon  1   2 , Pierre-Régis Burgel  1   2   3
Affiliations
Comment

Change in Lung Function after Initiation of Elexacaftor-Tezacaftor-Ivacaftor: Do Not Forget Anatomy!

Clémence Martin et al. Am J Respir Crit Care Med. .
No abstract available

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Comment in

Comment on

  • Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in People with Cystic Fibrosis: A Clinical Trial.
    Nichols DP, Paynter AC, Heltshe SL, Donaldson SH, Frederick CA, Freedman SD, Gelfond D, Hoffman LR, Kelly A, Narkewicz MR, Pittman JE, Ratjen F, Rosenfeld M, Sagel SD, Schwarzenberg SJ, Singh PK, Solomon GM, Stalvey MS, Clancy JP, Kirby S, Van Dalfsen JM, Kloster MH, Rowe SM; PROMISE Study group. Nichols DP, et al. Am J Respir Crit Care Med. 2022 Mar 1;205(5):529-539. doi: 10.1164/rccm.202108-1986OC. Am J Respir Crit Care Med. 2022. PMID: 34784492 Free PMC article.

References

    1. Nichols DP, Paynter AC, Heltshe SL, Donaldson SH, Frederick CA, Freedman SD, et al. PROMISE Study group Clinical effectiveness of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis: a clinical trial. Am J Respir Crit Care Med . 2022;205:529–539. - PMC - PubMed
    1. Esther CR, Jr, Muhlebach MS, Ehre C, Hill DB, Wolfgang MC, Kesimer M, et al. Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis. Sci Transl Med . 2019;11:eaav3488. - PMC - PubMed
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    1. Burgel PR, Montani D, Danel C, Dusser DJ, Nadel JA. A morphometric study of mucins and small airway plugging in cystic fibrosis. Thorax . 2007;62:153–161. - PMC - PubMed
    1. Boon M, Verleden SE, Bosch B, Lammertyn EJ, McDonough JE, Mai C, et al. Morphometric analysis of explant lungs in cystic fibrosis. Am J Respir Crit Care Med . 2016;193:516–526. - PubMed