FV reports grants from the US Agency of International Development, Unitaid, AIDS Fonds, and the South African Medical Research Council; non-financial support from Gilead, ViiV Healthcare, and MSD; personal fees from Gilead, ViiV, Mylan, Merk, Adcock-Ingram, Aspen, Abbott, Roche, Johnson & Johnson, Virology Education; and other support from Merck and Johnson & Johnson, outside the submitted work. All other authors declare no competing interests. The findings and conclusions in this systematic review are those of the authors and do not necessarily represent the official position of the funding agencies. This work has been supported by the President's Emergency Plan for AIDS Relief through the Centers for Disease Control and Prevention.