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Clinical Trial
. 1978 Jun;85(6):594-606.
doi: 10.1016/s0161-6420(78)35643-8.

The effect of calcium dobesilate on nonproliferative diabetic retinopathy: a controlled study

Clinical Trial

The effect of calcium dobesilate on nonproliferative diabetic retinopathy: a controlled study

R L Stamper et al. Ophthalmology. 1978 Jun.

Abstract

Two independent, double-masked, controlled studies were made to evaluate the efficacy of calcium dobesilate for the treatment of nonproliferative diabetic retinopathy. Forty-two patients underwent a six-month crossover evaluation while receiving calcium dobesilate (750 mg per day) and placebo in random order. Thirty-six patients received calcium dobesilate (1,000 mg per day) or placebo for one year. Evaluation by clinical examination, fluorescein angiography, angiography, and fundus photography failed to demonstrate any beneficial effect of calcium dobesilate.

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