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. 2022 Apr 1;17(4):e0266006.
doi: 10.1371/journal.pone.0266006. eCollection 2022.

Relationship between dynamic changes of peri-procedure anxiety and short-term prognosis in patients undergoing elective percutaneous coronary intervention for coronary heart disease: A single-center, prospective study

Yao-Yao Hu  1 , Ya-Jing Cai  2 , Xin Jiang  3 , Fang-Ying Mao  4 , Jing Zhang  4 , Lin Liu  1 , Qing Wu  1 , Xiao-Hua Wang  1
Affiliations

Relationship between dynamic changes of peri-procedure anxiety and short-term prognosis in patients undergoing elective percutaneous coronary intervention for coronary heart disease: A single-center, prospective study

Yao-Yao Hu et al. PLoS One. .

Abstract

Background: Patients with coronary heart disease (CHD) often experience anxiety, but the current studies on anxiety mostly focused on a certain point in time. Therefore, this study aimed to investigate the dynamic changes of peri-procedure anxiety, status of post-procedure quality of life, and cardiovascular readmission rates in patients with CHD who undergoing elective percutaneous coronary intervention (PCI), and to analyze the influence of peri-procedure anxiety on quality of life and readmission rate after PCI.

Methods: This prospective study was conducted at Changshu NO.1 People's Hospital. A total of 220 patients with CHD undergoing elective PCI were selected as study subjects. The general information, clinical data, anxiety, quality of life and readmission of patients were collected. Multivariate linear regression was used to examine the effect of peri-procedure anxiety on quality of life, and multivariate logistic regression was used to analyze the influence of peri-procedure anxiety on readmission rate.

Results: This study showed the anxiety scores at hospitalization appointment(T1), 3 days before procedure(T2), 1 day before procedure(T3), 1 day after procedure(T4) were 57(55,61),64(61,68),54(51.58), and 54(50,60), respectively. And, at 3 months and 6 months after PCI, the scores of Seattle Angina Questionnaire (SAQ) were 346.61(319.06,366.52) and 353.34(334.18,372.84) respectively. During 6 months follow-up, 54 cases were readmitted, with a readmission rate of 25.5%. Statistical analysis showed that T1 with anxiety (P = 0.002) and T2 with anxiety (P = 0.024) were independent risk factors for treatment satisfaction at 3 months after PCI. Anxiety in T4 (P = 0.005) was an independent risk factor on the angina frequency at 6 months after PCI. T2 with anxiety (B = 1.445, P = 0.010, 95%CI:1.409-12.773) and T4 without anxiety (B = -1.587, P = 0.042, 95%CI:-0.044-0.941) were risk factors affecting readmission for cardiovascular reasons within 6 months.

Conclusion: Patient anxiety at T1 and T2 affects the treatment satisfaction dimension of the SAQ at 3 months after PCI, and anxiety at T4 affects the angina frequency dimension of the SAQ at 6 months after PCI. Anxiety at T2 and no anxiety at T4 increase short-term readmission rates. In the future, interventions should be strengthened at various time points in the peri-procedure period to improve post-procedure rehabilitation effect.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Flow chart of recruitment and follow-up for the entire study.
PCI = percutaneous coronary intervention; SAQ = Seattle Angina Questionnaire.
See this image and copyright information in PMC

References

    1. Committee of experts on rational drug use of national health commission of the P.R China, Chinese pharmacists association. Guidelines for rational drug use in coronary heart disease. Chinese Journal of the Frontiers of Medical Science(Electronic Version). 2016;8(6):19–108.
    1. GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1736–1788. doi: 10.1016/S0140-6736(18)32203-7 - DOI - PMC - PubMed
    1. Hu SS, Gao RL, Li S, Zhu ML, Wang W, Wang YG, et al.. Summary of the 2018 Report on Cardiovascular Diseases in China. Chinese Circulation Journal.2019;34(3):209–220.
    1. Zhang XC, Yu XZ, Chen FY, Zhu HD. Guide for Rapid Emergency Treatment of Acute Coronary Syndrome (2019). Chinese Journal of Emergency Medicine.2019;39(04):301–308.
    1. Han YL. Rethinking of antithrombotic therapy in perioperative period of PCI-Interpretation of China PCI guidelines (2016). Chinese Journal of Health Care and Medicine.2016;18(5):349–351.

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