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Editorial
. 2022 Jun;66(6):596-597.
doi: 10.1165/rcmb.2022-0040ED.

TBK1's Role in Bacterial Pneumonia: Perhaps More than Macrophages and IFNs

Facundo Fiocca Vernengo  1 , Bastian Opitz  1   2
Affiliations
Editorial

TBK1's Role in Bacterial Pneumonia: Perhaps More than Macrophages and IFNs

Facundo Fiocca Vernengo et al. Am J Respir Cell Mol Biol. 2022 Jun.
No abstract available

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Figures

Figure 1.
Figure 1.
Schematic model representing the role of TBK1 in pneumococcal pneumonia in mice. After intranasal S. pneumoniae infection, TBK1-deficient mice show unaltered neutrophil recruitment into lungs but reduced neutrophilic ROS production, decreased pulmonary production of proinflammatory mediators, slightly higher bacterial loads in the lung, and increased mortality compared with control animals. Illustrations were partially created using templates from www.motifolio.com. ROS = reactive oxygen species; TBK1 = TANK-binding kinase 1.
See this image and copyright information in PMC

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References

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