Clinical Relevance of the Microbiome in Pediatric Skin Disease: A Review

Abstract

The human microbiome encompasses the microorganisms that live in and on the body. During the prenatal and infantile periods, foundations for the cutaneous and gut microbiomes are being established and refined concurrently with the development of immune function. Herein, we review the relevance of the microbiome to 5 conditions commonly encountered in pediatric dermatology: acne, alopecia areata, atopic dermatitis, psoriasis, and seborrheic dermatitis. Understanding the role microbes play in these conditions may establish the groundwork for future therapeutic interventions.

Keywords: Acne; Alopecia areata; Atopic dermatitis; Eczema; Microbiome; Pediatric; Psoriasis; Seborrheic dermatitis.