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. 2022 Mar 11:10:818164.
doi: 10.3389/fped.2022.818164. eCollection 2022.

Association Between Neonatal Arrhythmia and Mortality and Recurrence: A Retrospective Study

Lihong Ran  1   2   3   4   5 , Jie Li  6 , Lei Bao  1   2   3   4   5 , Long Chen  1   2   3   4   5
Affiliations

Association Between Neonatal Arrhythmia and Mortality and Recurrence: A Retrospective Study

Lihong Ran et al. Front Pediatr. .

Abstract

Objective: The aim of the present study was to explore the association between neonatal arrhythmia (NA) and mortality and recurrence.

Methods: A single-center, retrospective study was performed between January 1, 2015, and December 31, 2019. Neonates with NA were eligible and divided into either benign or non-benign groups. The primary outcomes were mortality and recurrence within 2 to 6 years.

Results: NA was diagnosed in 189 patients (0.39%) after screening 47,911 hospitalized neonates, and 10 of them did not finish the follow-up. Finally, 179 neonates were included into the final analysis (58 in the non-benign NA and 121 in the benign NA groups). The incidences of death and recurrence for NA were 5.59% (10/179) and 18.44% (33/179). Compared with neonates with benign NA, those neonates with non-benign NA were shown higher rates of death (13.79% vs. 1.65%; odds ratio [OR], 5.73; 95% confidence interval [CI], 1.07-31.01; p = 0.04) and recurrence (44.83% vs. 5.79%; OR, 8.49; 95% CI, 3.12-23.08; p < 0.001).

Conclusions: Neonates with non-benign NA were shown higher rates of death and recurrence when compared with benign NA. Because of high recurrence, more attention was needed in neonates with non-benign NA after discharge.

Keywords: arrhythmia; follow-up; mortality; neonatal intensive care unit; neonates; recurrence.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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References

    1. Tanel RE, Rhodes LA. Fetal and neonatal arrhythmias. Clin Perinatol. (2001) 28:187–207. 10.1016/S0095-5108(05)70074-9 - DOI - PubMed
    1. Ban JE. Neonatal arrhythmias: diagnosis, treatment, and clinical outcome. Korean J Pediatr. (2017) 60:344. 10.3345/kjp.2017.60.11.344 - DOI - PMC - PubMed
    1. Jaeggi EO, Hman A. Fetal and neonatal arrhythmias. Clin Perinatol. (2016) 43:99–112. 10.1016/j.clp.2015.11.007 - DOI - PubMed
    1. Dubin AM. Arrhythmias in the newborn. Neoreviews. (2000) 1:e146–51. 10.1542/neo.1-8-e146 - DOI
    1. Moura C, Vieira A, Guimares H, Areias JC. Perinatal arrhythmias–diagnosis and treatment. Rev Port Cardiol. (2002) 21:45–55. - PubMed

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