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Editorial
. 2021 Nov 25;2(11):1693-1695.
doi: 10.34067/KID.0006232021.

Untangling the Association between Anemia Treatment and Stroke Risk in CKD

Jay B Wish  1
Affiliations
Editorial

Untangling the Association between Anemia Treatment and Stroke Risk in CKD

Jay B Wish. Kidney360. .
No abstract available

Keywords: anemia; chronic kidney disease; dialysis; erythropoietin; hemodialysis; hypoxia-inducible factor; iron; stroke.

PubMed Disclaimer

Conflict of interest statement

J.B. Wish reports advisory boards for Akebia, AstraZeneca, CSL Behring, Otsuka, Rockwell Medical, and Vifor Pharma; consulting for Fibrogen; and speakers bureaus for Akebia and AstraZeneca.

Comment on

References

    1. Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, Feyzi JM, Ivanovich P, Kewalramani R, Levey AS, Lewis EF, McGill JB, McMurray JJ, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, Toto R; TREAT Investigators : A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med 361: 2019–2032, 2009. 10.1056/NEJMoa0907845 - DOI - PubMed
    1. Amgen : Epogen label, revised 9/2017, 2017. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/103234s5363s53.... Accessed September 25, 2021
    1. Parfrey PS, Foley RN, Wittreich BH, Sullivan DJ, Zagari MJ, Frei D: Double-blind comparison of full and partial anemia correction in incident hemodialysis patients without symptomatic heart disease. J Am Soc Nephrol 16: 2180–2189, 2005. 10.1681/ASN.2004121039 - DOI - PubMed
    1. Bello NA, Lewis EF, Desai AS, Anand IS, Krum H, McMurray JJ, Olson K, Solomon SD, Swedberg K, van Veldhuisen DJ, Young JB, Pfeffer MA: Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease. Eur J Heart Fail 17: 1201–1207, 2015. 10.1002/ejhf.412 - DOI - PMC - PubMed
    1. Singh AK, Szczech L, Tang KL, Barnhart H, Sapp S, Wolfson M, Reddan D; CHOIR Investigators : Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 355: 2085–2098, 2006. 10.1056/NEJMoa065485 - DOI - PubMed

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