Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D
- PMID: 3537648
- DOI: 10.1016/0306-9877(86)90010-1
Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D
Abstract
A group of young patients having multiple sclerosis was treated with dietary supplements containing calcium, magnesium and vitamin D for a period of one to two years. The experimental design employed self-pairing: the response of each patient was compared with his/her own case history as control. The number of exacerbations observed during the program was less than one half the number expected from case histories. No side effects were apparent. The dietary regimen may offer a new means of controlling the exacerbation rate in MS, at least for younger patients. The results tend to support a theory of MS which states that calcium and magnesium are important in the development, structure and stability of myelin.
Similar articles
-
Reported Dietary Intake, Disparity between the Reported Consumption and the Level Needed for Adequacy and Food Sources of Calcium, Phosphorus, Magnesium and Vitamin D in the Spanish Population: Findings from the ANIBES Study.Nutrients. 2017 Feb 21;9(2):168. doi: 10.3390/nu9020168. Nutrients. 2017. PMID: 28230782 Free PMC article.
-
Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage.Exp Neurol. 2013 Nov;249:39-48. doi: 10.1016/j.expneurol.2013.08.002. Epub 2013 Aug 13. Exp Neurol. 2013. PMID: 23954214
-
Dietary calcium and mineral/vitamin supplementation: a controversial problem.J Int Med Res. 1999 Jan-Feb;27(1):1-14. doi: 10.1177/030006059902700101. J Int Med Res. 1999. PMID: 10417956 Review.
-
Lifestyle modifications to prevent and control hypertension. 6. Recommendations on potassium, magnesium and calcium. Canadian Hypertension Society, Canadian Coalition for High Blood Pressure Prevention and Control, Laboratory Centre for Disease Control at Health Canada, Heart and Stroke Foundation of Canada.CMAJ. 1999 May 4;160(9 Suppl):S35-45. CMAJ. 1999. PMID: 10333852 Free PMC article.
-
Supplementation and therapeutic use of vitamin D in patients with multiple sclerosis: consensus of the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology.Arq Neuropsiquiatr. 2014 Feb;72(2):152-6. doi: 10.1590/0004-282X20130252. Arq Neuropsiquiatr. 2014. PMID: 24604370 English, Portuguese.
Cited by
-
Environmental factors and their timing in adult-onset multiple sclerosis.Nat Rev Neurol. 2010 Mar;6(3):156-66. doi: 10.1038/nrneurol.2010.1. Epub 2010 Feb 16. Nat Rev Neurol. 2010. PMID: 20157307 Review.
-
Multiple sclerosis and vitamin D: a review and recommendations.Curr Neurol Neurosci Rep. 2010 Sep;10(5):389-96. doi: 10.1007/s11910-010-0131-5. Curr Neurol Neurosci Rep. 2010. PMID: 20556546 Review.
-
Dose-related effects of vitamin D on immune responses in patients with clinically isolated syndrome and healthy control participants: study protocol for an exploratory randomized double- blind placebo-controlled trial.Trials. 2013 Aug 27;14:272. doi: 10.1186/1745-6215-14-272. Trials. 2013. PMID: 23981773 Free PMC article. Clinical Trial.
-
Dose-Dependent Effect of a New Biotin Compound in Hippocampal Remyelination in Rats.Mol Neurobiol. 2025 May;62(5):6503-6520. doi: 10.1007/s12035-025-04686-y. Epub 2025 Jan 16. Mol Neurobiol. 2025. PMID: 39821844 Free PMC article.
-
Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia.J Neurol. 2007 May;254(5):581-90. doi: 10.1007/s00415-006-0315-8. Epub 2007 Apr 11. J Neurol. 2007. PMID: 17426912
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical