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. 1986;324(6095):341-5.
doi: 10.1038/324341a0.

Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes

C W Pikielny, B C Rymond, M Rosbash

Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes

C W Pikielny et al. Nature. 1986.

Abstract

Three splicing complexes formed with a yeast pre-messenger RNA during in vitro splicing can be resolved by non-denaturing gel electrophoresis after incubation in the presence of non-specific competitor RNA. The time course of the appearance of these complexes and their composition suggest that they represent an ordered pathway of splicing complex assembly.

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