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Review
. 2022 Mar;9(1):e001225.
doi: 10.1136/bmjresp-2022-001225.

BTS clinical statement for the diagnosis and management of ocular tuberculosis

Onn Min Kon  1   2 , Nicholas Beare  3   4 , David Connell  5 , Erika Damato  6 , Thomas Gorsuch  7 , Guy Hagan  8 , Felicity Perrin  9 , Harry Petrushkin  10 , Jessica Potter  11 , Charanjit Sethi  12 , Miles Stanford  13
Affiliations
Review

BTS clinical statement for the diagnosis and management of ocular tuberculosis

Onn Min Kon et al. BMJ Open Respir Res. 2022 Mar.

Abstract

The BTS clinical statement for the diagnosis and management of ocular tuberculosis (TB) draws on the expertise of both TB and and ophthalmic specialists to outline the current understanding of disease pathogenesis, diagnosis and management in adults. Published literature lacks high-quality evidence to inform clinical practice and there is also a paucity of data from animal models to elucidate mechanisms of disease. However, in order to improve and standardise patient care, this statement provides consensus points with the currently available data and agreed best practice.

Keywords: tuberculosis.

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Conflict of interest statement

Competing interests: Funding has been declared from: DC, Insmed; OMK Boehringer Ingelheim, Oxford Immunotech, Cepheid, Qiagen; alal other authors have no declared interests.

Figures

Figure 1
Figure 1
Management pathway. AFB, acid–fast bacilli; ANA, antinucleaer antibody; ANCA, antineutrophil cytoplasmic antibody; ATT, antituberculous therapy; CNS, central nervous system; CXR, chest X-ray; EBUS, endobronchial ultrasound; IGRAs, interferon-gamma release-assays; LTBI, latent TB infection; OTB, ocular TB; PET, positron emission tomography; RCT, randomised controlled trial; TB, tuberculosis; TNF, tumour necrosis factor; U&E, urea and electrolytes.
Figure 2
Figure 2
Anatomical classification of uveitis depicting structures affected in anterior, intermediate and posterior uveitis.
See this image and copyright information in PMC

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