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Published Erratum
. 2022 Apr 6;12(1):5740.
doi: 10.1038/s41598-022-09558-2.

Author Correction: Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534

Xiaohua Xue  1 , Aimee De Leon-Tabaldo  2 , Rosa Luna-Roman  2 , Glenda Castro  3 , Michael Albers  4 , Freddy Schoetens  2 , Samuel DePrimo  2 , Damayanthi Devineni  3 , Thomas Wilde  3 , Steve Goldberg  2 , Olaf Kinzel  4 , Thomas Hoffmann  4 , Anne M Fourie  2 , Robin L Thurmond  5
Affiliations
Published Erratum

Author Correction: Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534

Xiaohua Xue et al. Sci Rep. .
No abstract available

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Figures

Figure 1
Figure 1
Structure and selectivity of JNJ-61803534 for inhibition of RORγt-driven transcription. (a) Structure of JNJ-61803534. (b) Activity of JNJ-61803534 in 1-hybrid reporter assays. HEK-293 T cells were transfected with vectors encoding RORγt, RORα or RORβ, respectively, fused with the GAL4 DNA binding domain. After incubation with compound overnight, luciferase signals were measured. JNJ-61803534 was tested at a starting concentration of 2 μM in three-fold serial dilutions in duplicate.
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